Area of research
Molecular Biology · Genetics
Research interest
Research interests include Biology, Cell biology, Stem cell, Induced pluripotent stem cell, Progenitor cell, and Organoid.
Altered Lipid Homeostasis in Mutant FUSR521H Astrocytes from HiPSCs
MyeliMAP: Studying Oligodendrocyte Function in Brain Networks
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology
Elevated α-synuclein levels inhibit mitophagic flux
Robotics-Driven Manufacturing of Cartilaginous Microtissues for Skeletal Tissue Engineering Applications
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
Large-scale perfused tissues via synthetic 3D soft microfluidics
From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions
Xenografted human microglia in response to Alzheimer’s disease Aβ pathology
Engineering neurovascular organoids with 3D printed microfluidic chips
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy
CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of <i>C9orf72</i> poly(PR) toxicity
HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations
<i>C9orf72</i> -derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility
Actuation enhances patterning in human neural tube organoids
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System
Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities
Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells
Organoid and microfluidics-based platforms for drug screening in COVID-19
PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells
A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model
HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines
Correction of CFTR function in intestinal organoids to guide treatment of cystic fibrosis
Comparing in vitro human liver models to in vivo human liver using RNA-Seq
Ex Vivo Mimicking of Inflammation in Organoids Derived From Patients With Ulcerative Colitis
Unraveling the transcriptional determinants of liver sinusoidal endothelial cell specialization
Functional expression and pharmacological modulation of TRPM3 in human sensory neurons
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods
Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells