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Keimpe Wierda

University of Copenhagen · DK
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Area of research
Cellular and Molecular Neuroscience · Cell Biology
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Cellular transport and secretion, Alzheimer's disease research and treatments, and Retinal Development and Disorders.
h-index
29
citations
3,840
works
66
NIH funding
primary concept
email

Recent publications

Intracortical bipolar stimulation allows selective activation of neuronal populations in the cortex
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 2position: middledoi
MyeliMAP: Studying Oligodendrocyte Function in Brain Networks
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 0position: middledoi
Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
Developmental Cell 2024cited by 40position: middledoi
Protocol to process fresh human cerebral cortex biopsies for patch-clamp recording and immunostaining
STAR Protocols 2024cited by 4position: firstdoi
Mitochondria metabolism sets the species-specific tempo of neuronal development
Science 2023cited by 279position: middledoi
<i>Helicobacter pylori</i>‐derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3‐C3aR signalling
Journal of Extracellular Vesicles 2023cited by 125position: middledoi
Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease
Nature Neuroscience 2023cited by 61position: middledoi
LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons
Cell 2023cited by 43position: middledoi
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
Nature Immunology 2022cited by 209position: middledoi
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy
Brain 2022cited by 140position: middledoi
AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model
EMBO Molecular Medicine 2022cited by 42position: middledoi
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
Neuron 2021cited by 78position: middledoi
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System
Stem Cell Reviews and Reports 2021cited by 50position: middledoi
Corticotropin-Releasing Factor Induces Functional And Structural Synaptic Remodelling In Acute Stress
bioRxiv (Cold Spring Harbor Laboratory) 2021cited by 2position: middledoi
Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
Nature Communications 2020cited by 66position: middledoi
Mapping the cell-surface proteome underlying hippocampal mossy fiber synapse identity
Greater South Information System 2019cited by 0position: middledoi
Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule‐associated protein TAU mutations which displays several phenotypes linked to neurodegeneration
Alzheimer s & Dementia 2018cited by 54position: middledoi
Tau association with synaptic vesicles causes presynaptic dysfunction
Nature Communications 2017cited by 449position: middledoi
The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors
Neuron 2015cited by 92position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Joris de Wit · Allen Institute for Brain Science7 papers (2015–2024)Kristel M. Vennekens · VIB-KU Leuven Center for Brain & Disease Research4 papers (2015–2023)Bart De Strooper · The Francis Crick Institute4 papers (2017–2022)Catherine M. Verfaillie · KU Leuven4 papers (2018–2025)Ine Vlaeminck · KU Leuven3 papers (2023–2024)Vasily Rybakin · National University of Singapore3 papers (2019–2021)Jeffrey N. Savas · Northwestern University3 papers (2015–2020)Natalia V. Gounko · VIB-KU Leuven Center for Brain & Disease Research3 papers (2019–2021)Nuno Apóstolo · University of Coimbra3 papers (2019–2021)Eline Creemers · KU Leuven2 papers (2021–2022)Lujia Zhou · Second Affiliated Hospital of Nanjing Medical University2 papers (2017–2022)Andreas Ebneth · Charité - Universitätsmedizin Berlin2 papers (2018–2021) · 2 papers (2018–2021)Matthew G. Holt · VIB-KU Leuven Center for Brain & Disease Research2 papers (2017–2022) · 2 papers (2023–2024)Jef Swerts · VIB-KU Leuven Center for Brain & Disease Research2 papers (2017–2021)Jolijn ten Bos · Utrecht University2 papers (2019–2020)Joseph McInnes · Baylor College of Medicine2 papers (2017–2021)Amélie Lejeune · Columbia University2 papers (2023–2024)Tom Theys · Stichting Epilepsie Instellingen Nederland2 papers (2023–2024)
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