Area of research
Molecular Biology · Infectious Diseases
Research interest
Research interests include Gut microbiota and health, Clostridium difficile and Clostridium perfringens research, Microbial Natural Products and Biosynthesis, and Drug Transport and Resistance Mechanisms.
Host metabolism balances microbial regulation of bile acid signalling
Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology
Dietary fiber is a critical determinant of pathologic ILC2 responses and intestinal inflammation
The gut microbiome regulates the clinical efficacy of sulfasalazine therapy for IBD-associated spondyloarthritis
Decoding the microbiome: advances in genetic manipulation for gut bacteria
Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation
Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome
Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression
Transferable Immunoglobulin A–Coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation
Adherent-invasive E. coli metabolism of propanediol in Crohn’s disease regulates phagocytes to drive intestinal inflammation
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells
Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its Structural Diversity