Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Biology, CRISPR, Cancer research, Computational biology, Cas9, and Gene.
Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma
Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling
Defining a Cancer Dependency Map
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2
Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting