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Jan Novák

University of Alabama at Birmingham Hospital · US
Area of research
Nephrology · Molecular Biology
Research interest
Research interests include Renal Diseases and Glomerulopathies, Glycosylation and Glycoproteins Research, Monoclonal and Polyclonal Antibodies Research, and Platelet Disorders and Treatments.
h-index
81
citations
22,015
works
338
NIH funding
primary concept
email

Recent publications

Proteinuria Trajectory and Disease Progression in Children and Adults with IgA Nephropathy/Vasculitis
Clinical Journal of the American Society of Nephrology 2025cited by 14position: middledoi
Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy
Journal of Clinical Investigation 2025cited by 12position: middledoi
Nitazoxanide and tizoxanide demonstrate high levels of <i>in vitro</i> activity against metronidazole-susceptible and metronidazole-resistant <i>Trichomonas vaginalis</i> clinical isolates
Microbiology Spectrum 2025cited by 5position: middledoi
Sparsentan ameliorates glomerular hypercellularity and inflammatory-gene networks induced by IgA1-IgG immune complexes in a mouse model of IgA nephropathy
American Journal of Physiology-Renal Physiology 2024cited by 13position: lastdoi
<i>O</i>-glycosylation of IgA1 and the pathogenesis of an autoimmune disease IgA nephropathy
Glycobiology 2024cited by 12position: firstdoi
IgA Nephropathy: Significance of IgA1-Containing Immune Complexes in Clinical Settings
Journal of Clinical Medicine 2024cited by 9position: lastdoi
Publisher Correction: Glycosylation in health and disease
Nature Reviews Nephrology 2024cited by 5position: lastdoi
Current Understanding of Complement Proteins as Therapeutic Targets for the Treatment of Immunoglobulin A Nephropathy
Drugs 2023cited by 22position: middledoi
Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases
iScience 2023cited by 15position: middledoi
LIF/JAK2/STAT1 Signaling Enhances Production of Galactose-Deficient IgA1 by IgA1-Producing Cell Lines Derived From Tonsils of Patients With IgA Nephropathy
Kidney International Reports 2023cited by 14position: middledoi
Colocalization of IgG and IgA Heavy Chains with Kappa and Lambda Light Chains in Glomerular Deposits of IgA Nephropathy Patients Using High-Resolution Confocal Microscopy and Correlation with Oxford MEST-C Scores
Journal of Clinical Medicine 2023cited by 14position: middledoi
Identification of Trichomonas vaginalis 5-Nitroimidazole Resistance Targets
Pathogens 2023cited by 10position: middledoi
Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits
Nature Communications 2022cited by 53position: middledoi
Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses
JCI Insight 2022cited by 48position: middledoi
Glomerular deposition of galactose-deficient IgA1-containing immune complexes via glomerular endothelial cell injuries
Nephrology Dialysis Transplantation 2022cited by 25position: middledoi
Cytokines and Production of Aberrantly <i>O</i> -Glycosylated IgA1, the Main Autoantigen in IgA Nephropathy
Journal of Interferon & Cytokine Research 2022cited by 12position: middledoi
Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy
iScience 2022cited by 12position: middledoi
Pathogenesis of IgA Nephropathy: Current Understanding and Implications for Development of Disease-Specific Treatment
Journal of Clinical Medicine 2021cited by 89position: middledoi
IgA vasculitis with nephritis: update of pathogenesis with clinical implications
Pediatric Nephrology 2021cited by 82position: middledoi
IgA glycosylation and immune complex formation in IgAN
Seminars in Immunopathology 2021cited by 76position: lastdoi
Experimental evidence of pathogenic role of IgG autoantibodies in IgA nephropathy
Journal of Autoimmunity 2021cited by 52position: lastdoi
Aberrantly Glycosylated IgA1 in IgA Nephropathy: What We Know and What We Don’t Know
Journal of Clinical Medicine 2021cited by 40position: middledoi
Immunoglobulin A Glycosylation and Its Role in Disease
Experientia supplementum 2021cited by 26position: middledoi
Transcription Factor β-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney
Cells 2021cited by 21position: middledoi
The Dual Endothelin Angiotensin Receptor Antagonist (DEARA) Sparsentan Protects from Glomerular Hypercellularity and Associated Immune/Inflammatory Gene Network Activity in a Model of IgA Nephropathy
Journal of the American Society of Nephrology 2021cited by 3position: lastdoi
A systematic review of the literature on mechanisms of 5-nitroimidazole resistance in<i>Trichomonas vaginalis</i>
Parasitology 2020cited by 74position: middledoi
Leukemia Inhibitory Factor Signaling Enhances Production of Galactose-Deficient IgA1 in IgA Nephropathy
Kidney Diseases 2020cited by 41position: lastdoi
Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation
Scientific Reports 2020cited by 34position: middledoi
Mass spectrometry for the identification and analysis of highly complex glycosylation of therapeutic or pathogenic proteins
Expert Review of Proteomics 2020cited by 18position: middledoi
Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies
iScience 2020cited by 11position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Bruce A. Julian · University of Alabama at Birmingham36 papers (2012–2023)Hitoshi Suzuki · University of Alabama at Birmingham26 papers (2012–2024)Matthew B. Renfrow · University of Alabama at Birmingham24 papers (2012–2024)Zina Moldoveanu · University of Alabama at Birmingham21 papers (2012–2024)Colin Reily · University of Alabama at Birmingham19 papers (2014–2024)Stacy Hall · University of Alabama at Birmingham17 papers (2012–2024)Milan Raška · University of Alabama at Birmingham16 papers (2012–2020) · 15 papers (2012–2023) · 12 papers (2012–2017)Ali G. Gharavi · Columbia University Irving Medical Center12 papers (2012–2021)Dana V. Rizk · University of Alabama at Birmingham10 papers (2015–2023)Robert Wyatt · University of Georgia10 papers (2012–2021)Jiří Městecký · University of Alabama at Birmingham9 papers (2012–2016)Rhubell Brown · University of Alabama at Birmingham9 papers (2012–2021)Krzysztof Kiryluk · Columbia College8 papers (2012–2021)Barbora Knoppová · University of Alabama at Birmingham7 papers (2016–2021)Kazuo Takahashi · University of Alabama at Birmingham7 papers (2014–2022)Todd J. Green · University of Alabama at Birmingham7 papers (2018–2024) · 7 papers (2012–2022)Lea Novak · University of Alabama at Birmingham7 papers (2012–2024)