Area of research
Molecular Biology · Hematology
Research interest
Research interests include Epigenetics and DNA Methylation, Acute Myeloid Leukemia Research, Protein Degradation and Inhibitors, and Ubiquitin and proteasome pathways.
Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain
Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.
High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program
Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma
BET bromodomain proteins regulate enhancer function during adipogenesis
Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression
BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis