Area of research
Molecular Biology · Genetics
Research interest
Research interests include RNA and protein synthesis mechanisms, CRISPR and Genetic Engineering, RNA Research and Splicing, and RNA modifications and cancer.
Machine learning predicts new anti-CRISPR proteins
Potent CRISPR-Cas9 inhibitors from <i>Staphylococcus</i> genomes
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
Systematic discovery of natural CRISPR-Cas12a inhibitors
Cotranscriptional folding of a riboswitch at nucleotide resolution
Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)
A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future
Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq
SHAPE-Seq 2.0: systematic optimization and extension of high-throughput chemical probing of RNA secondary structure with next generation sequencing
The centrality of RNA for engineering gene expression