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Orna Issler

Neurosciences Institute ·
Area of research
Behavioral Neuroscience · Biological Psychiatry
Research interest
Research interests include Stress Responses and Cortisol, Tryptophan and brain disorders, MicroRNA in disease regulation, and Adipose Tissue and Metabolism.
h-index
26
citations
4,196
works
59
NIH funding
primary concept
email

Recent publications

Mono-methylation of lysine 27 at histone 3 confers lifelong susceptibility to stress
Neuron 2024cited by 24position: middledoi
Sex-Specific Regulation of Stress Susceptibility by the Astrocytic Gene <i>Htra1</i>
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 6position: middledoi
Male and female behavioral variability and morphine response in C57BL/6J, DBA/2J, and their BXD progeny following chronic stress exposure
Scientific Reports 2024cited by 5position: middledoi
Change-of-mind neuroeconomic decision-making is modulated by LINC00473 in medial prefrontal cortex in a sex-dependent manner
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 3position: middledoi
Male and female variability in response to chronic stress and morphine in C57BL/6J, DBA/2J, and their BXD progeny
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 1position: middledoi
Monomethylation of Lysine 27 at Histone 3 Confers Lifelong Susceptibility to Stress
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 11position: middledoi
The long noncoding RNA FEDORA is a cell type– and sex-specific regulator of depression
Science Advances 2022cited by 56position: firstdoi
Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression
Molecular Psychiatry 2022cited by 51position: lastdoi
Crystallin Mu in Medial Amygdala Mediates the Effect of Social Experience on Cocaine Seeking in Males but Not in Females
Biological Psychiatry 2022cited by 20position: middledoi
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons
Nature Neuroscience 2021cited by 114position: middledoi
Sperm Transcriptional State Associated with Paternal Transmission of Stress Phenotypes
Journal of Neuroscience 2021cited by 27position: middledoi
Sex-Specific Role for SLIT1 in Regulating Stress Susceptibility
Biological Psychiatry 2021cited by 26position: middledoi
Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons
Nature Neuroscience 2021cited by 6position: middledoi
The Long Noncoding RNA FEDORA is a Cell-Type- and Sex-Specific Regulator of Depression
bioRxiv (Cold Spring Harbor Laboratory) 2021cited by 5position: firstdoi
Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression
Neuron 2020cited by 165position: firstdoi
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex
Nature Neuroscience 2019cited by 122position: middledoi
Unraveling the epigenetic landscape of depression: focus on early life stress
Dialogues in Clinical Neuroscience 2019cited by 107position: middledoi
Gadd45b mediates depressive-like role through DNA demethylation
Scientific Reports 2019cited by 52position: middledoi
Molecular characterization of the resilient brain
Elsevier eBooks 2019cited by 3position: firstdoi
Estrogen receptor α drives pro-resilient transcription in mouse models of depression
Nature Communications 2018cited by 110position: middledoi
The molecular basis for sex differences in depression susceptibility
Current Opinion in Behavioral Sciences 2018cited by 18position: firstdoi
<i>Zfp189</i> Mediates Stress Resilience Through a CREB-Regulated Transcriptional Network in Prefrontal Cortex
bioRxiv (Cold Spring Harbor Laboratory) 2018cited by 3position: middledoi
Sex-specific transcriptional signatures in human depression
Nature Medicine 2017cited by 798position: middledoi
Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2
Science 2017cited by 413position: middledoi
Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2
Biological Psychiatry 2017cited by 62position: middledoi
Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors
Neuropsychopharmacology 2017cited by 60position: middledoi
159. The Largest Number of Cocaine-Induced Changes in Chromatin Modifications Are Associated with Increased Expression and 3D Looping of Auts2
Biological Psychiatry 2017cited by 0position: middledoi
Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility
Neuron 2016cited by 352position: middledoi
Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine
Scientific Reports 2016cited by 262position: middledoi
Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior
Proceedings of the National Academy of Sciences 2016cited by 66position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Eric J. Nestler · Allen Institute for Brain Science26 papers (2016–2024)Deena M. Walker · Oregon Health & Science University17 papers (2016–2024)Li Shen · Allen Institute for Brain Science16 papers (2016–2023)Caleb J. Browne · Allen Institute for Brain Science13 papers (2021–2024)Yentl Y. van der Zee · Allen Institute for Brain Science12 papers (2021–2024)Angélica Torres‐Berrío · Allen Institute for Brain Science11 papers (2019–2024)Eric M. Parise · Allen Institute for Brain Science11 papers (2018–2024)Catherine J. Peña · Princeton University10 papers (2016–2022)Scott J. Russo · Allen Institute for Brain Science9 papers (2016–2024)Aarthi Ramakrishnan · Allen Institute for Brain Science9 papers (2021–2023)Hope Kronman · NYU Langone Health8 papers (2017–2024)Benoît Labonté · Université Laval8 papers (2016–2022)Casey K. Lardner · Horace Mann School8 papers (2021–2024)Rachael L. Neve · Massachusetts General Hospital7 papers (2016–2021)Hannah M. Cates · Icahn School of Medicine at Mount Sinai6 papers (2016–2022)Marine Salery · Allen Institute for Brain Science5 papers (2018–2024)Zachary S. Lorsch · Icahn School of Medicine at Mount Sinai5 papers (2016–2024)Arthur Godino · Allen Institute for Brain Science4 papers (2021–2024)Simone Sidoli · Albert Einstein College of Medicine4 papers (2021–2024)Lyonna F. Parise · Allen Institute for Brain Science4 papers (2021–2024)