Catherijne A. J. Knibbe

Pharmacogenetics in perioperative care: Understanding the impact of genetic variants on patient management.

The prevalence of medication-related hospital readmissions after bariatric surgery: a retrospective observational study.

Semi-Physiological Population Pharmacokinetic Modeling of Oral and Intravenous Paracetamol to Quantify Presystemic Metabolism and Enterohepatic Recirculation.

All You Need to Know About Allometric Scaling: An Integrative Review on the Theoretical Basis, Empirical Evidence, and Application in Human Pharmacology.

Model-Informed Dose Optimization of Pazopanib in Real-World Patients with Cancer.

The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling.

The Drug Titration Paradox in the Presence of Intra-Individual Variation: Can we Estimate the True Concentration-Effect Relationship?

Patients in Clinical Trials are Sub-Optimally Protected for Drug-Drug Interactions: A Call for Action.

Correction: "Simultaneous Pharmacokinetic Modeling of Gentamicin, Tobramycin and Vancomycin Clearance From Neonates to Adults: Towards a Semi-physiological Function for Maturation in Glomerular Filtration".

Spatial Pharmacokinetic and Pharmacodynamic Modeling in Airway Mucus.

Changes in the Fraction Metabolized in Children Younger than Four Years; When is Clearance Scaling for the Dominant Elimination Route in Adults Appropriate?

A Systematic Evaluation of the Dosing Regimens for Approved Targeted Therapies and Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma From a Project OPTIMUS Perspective.

A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite.

Colistin resistance dynamics in <i>Pseudomonas aeruginosa</i> under biofilm and planktonic growth.

The influence of heteroresistance, growth and antibiotic selection in shaping the invasion dynamics of colistin resistant <i>Pseudomonas aeruginosa</i>

Virtual Patient Simulation Using Copula Modeling.

Patients with Obesity Should be Recognised as a Special Patient Population During Drug Development of Antibacterial and Antifungal Agents; A Call to Action.

Generation of realistic virtual adult populations using a model-based copula approach.

Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial.

How to Dose Vancomycin in Overweight and Obese Patients with Varying Renal (Dys)function in the Novel Era of AUC 400-600 mg·h/L-Targeted Dosing.

When will the Glomerular Filtration Rate in Former Preterm Neonates Catch up with Their Term Peers?

Ex vivo gut-hepato-biliary organ perfusion model to characterize oral absorption, gut-wall metabolism, pre-systemic hepatic metabolism and biliary excretion; application to midazolam.

Impact of Obesity on Hepatic Drug Clearance: What are the Influential Variables?

Aggregate Formation and Antibody Stability in Infusion Bags: The Impact of Manual and Robotic Compounding of Monoclonal Antibodies.

Analysis of production time and capacity for manual and robotic compounding scenarios for parenteral hazardous drugs.

Clinical Guidance for Dosing and Monitoring Oral Antihormonal Drugs in Patients with Breast Cancer After Roux-en-Y Gastric Bypass.

Population Pharmacokinetics of Cabozantinib in Metastatic Renal Cell Carcinoma Patients: Towards Drug Expenses Saving Regimens.

Documentation of the Patient Characteristics Morbid Obesity and Bariatric Surgery in the Hospital Information System and the Influence on the Number of Medication-Related Problems.

Generation of realistic virtual adult populations using a model-based copula approach

Pooled Population Pharmacokinetic Analysis and Dose Recommendations for Ciprofloxacin in Intensive Care Unit Patients with Obesity.