Area of research
Pharmacology · Computational Theory and Mathematics
Research interest
Research interests include Antibiotics Pharmacokinetics and Efficacy, Computational Drug Discovery Methods, Drug Transport and Resistance Mechanisms, and Antibiotic Resistance in Bacteria.
Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety.
Copulas for Covariate Simulation in Pharmacometrics.
Clinical prevalence of collateral sensitivity: a systematic exploration of multicentre antimicrobial surveillance data.
Assessing the impact of bacterial heterogeneity on bacteriophage population dynamics.
Model-based optimisation for teicoplanin dosing in patients undergoing maintenance haemodialysis.
Experimental and virus-specific drivers of EC<sub>50</sub> variability in antiviral assays evaluated using mathematical modeling.
The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles.
Clinical Pharmacokinetics of Psilocin After Psilocybin Administration: A Systematic Review and Post-Hoc Analysis.
Clinical Pharmacokinetics of N,N-Dimethyltryptamine (DMT): A Systematic Review and Post-hoc Analysis.
Nutrient conditions affect antimicrobial pharmacodynamics in <i>Pseudomonas aeruginosa</i>.
Pharmacodynamics of interspecies interactions in polymicrobial infections.
Do P-glycoprotein-mediated drug-drug interactions at the blood-brain barrier impact morphine brain distribution?
Aggregate data modelling: a fast implementation for fitting pharmacometrics models to summary-level data in R
Spatial Pharmacokinetic and Pharmacodynamic Modeling in Airway Mucus.
Beta-endorphin is the key endogenous opioid influencing morphine µ-opioid receptor occupancy in rat hypothalamus: a binding kinetic model analysis.
Nutrients drive the antibiotic-specific evolution of resistance in Pseudomonasaeruginosa.
Prolonged anoxic exposure impacts antibiotic sensitivity profiles of Pseudomonas aeruginosa.
Correction: Clinical Pharmacokinetics of Psilocin After Psilocybin Administration: A Systematic Review and Post‑Hoc Analysis.
Colistin resistance dynamics in <i>Pseudomonas aeruginosa</i> under biofilm and planktonic growth.
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity.
Virtual Patient Simulation Using Copula Modeling.
Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers
Model-based dose optimization framework for bedaquiline, pretomanid and linezolid for the treatment of drug-resistant tuberculosis.
QSPRpred: a Flexible Open-Source Quantitative Structure-Property Relationship Modelling Tool.
Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers.
Interplay of virulence factors shapes ecology and treatment outcomes in polymicrobial infections.
Non-linear blood-brain barrier transport and dosing strategies influence receptor occupancy ratios of morphine and its metabolites in pain matrix.
Quantitative modeling of tumor dynamics and development of drug resistance in non-small cell lung cancer patients treated with erlotinib.
Interspecies interactions alter the antibiotic sensitivity of <i>Pseudomonas aeruginosa</i>.
Longitudinal metabolite profiling of Streptococcus pneumoniae-associated community-acquired pneumonia.