Area of research
Immunology · Infectious Diseases
Research interest
Research interests include Immunodeficiency and Autoimmune Disorders, Immune Cell Function and Interaction, T-cell and B-cell Immunology, and COVID-19 Clinical Research Studies.
TGFβ links EBV to multisystem inflammatory syndrome in children
Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature
Human LY9 governs CD4 <sup>+</sup> T cell IFN-γ immunity to <i>Mycobacterium tuberculosis</i>
FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants
Primary and secondary defects of the thymus
IL-7–dependent and –independent lineages of IL-7R–dependent human T cells
A pleiotropic recurrent dominant <i>ITPR3</i> variant causes a complex multisystemic disease
Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling
Additional file 2 of Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
Clinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations
Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq
Autoantibodies Against Proteins Previously Associated With Autoimmunity in Adult and Pediatric Patients With COVID-19 and Children With MIS-C
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child
Neutralizing type‐I interferon autoantibodies are associated with delayed viral clearance and intensive care unit admission in patients with COVID‐19
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy
Sex differences in a cohort of COVID-19 Italian patients hospitalized during the first and second pandemic waves
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia
<i>Nfkb2</i> variants reveal a p100-degradation threshold that defines autoimmune susceptibility
Comprehensive Genetic Results for Primary Immunodeficiency Disorders in a Highly Consanguineous Population
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice