Heinrich Leonhardt

The HP1 box of KAP1 organizes HP1α for silencing of endogenous retroviral elements in embryonic stem cells

Effective eradication of acute myeloid leukemia stem cells with FLT3-directed antibody-drug conjugates

ARID1A mutations protect follicular lymphoma from FAS-dependent immune surveillance by reducing RUNX3/ETS1-driven FAS-expression

Orthogonal Site-Specific Dual Bioconjugation of Aryl and Alkyl Thiols

Targeted CD47 checkpoint blockade using a mesothelin-directed antibody construct for enhanced solid tumor-specific immunotherapy

Altered enhancer-promoter interaction leads to <i>MNX1</i> expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)

Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML

CD33-TIM3 Dual CAR T Cells: Enhancing Specificity While Maintaining Efficacy Against AML

Altered enhancer-promoter interaction leads to <i>MNX1</i> expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)

Spatial organization of transcribed eukaryotic genes

TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation

Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML

MeCP2-induced heterochromatin organization is driven by oligomerization-based liquid–liquid phase separation and restricted by DNA methylation

FUS-dependent liquid–liquid phase separation is important for DNA repair initiation

Cristae-dependent quality control of the mitochondrial genome

Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML

Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress

ARID1A Controls a Novel Transcriptional Network Regulating FAS in Follicular Lymphoma

A protein assembly mediates Xist localization and gene silencing

Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma

Super-resolution in situ analysis of active ribosomal DNA chromatin organization in the nucleolus

Cohesin depleted cells rebuild functional nuclear compartments after endomitosis

Regulatory encoding of quantitative variation in spatial activity of a <i>Drosophila</i> enhancer

Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells

Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy

P04.04 Multifunctional antibody construct for <i>in vivo</i> targeting of dendritic cells as a therapeutic vaccination strategy in AML

Heterochromatin drives compartmentalization of inverted and conventional nuclei

BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples

Cysteine‐Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations

Loss of KDM6A confers drug resistance in acute myeloid leukemia