Area of research
Radiology, Nuclear Medicine and Imaging · Oncology
Research interest
Research interests include Camptothecin, Linker, In vivo, Chemistry, Myeloid leukemia, and Leukemia.
Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates
Effective eradication of acute myeloid leukemia stem cells with FLT3-directed antibody-drug conjugates
Orthogonal Site-Specific Dual Bioconjugation of Aryl and Alkyl Thiols
Design and Evaluation of Phosphonamidate-Linked Exatecan Constructs for Highly Loaded, Stable, and Efficacious Antibody–Drug Conjugates
Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML
Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells
Evaluation of a Bifunctional Sirpα-CD123 Fusion Antibody for the Elimination of Acute Myeloid Leukemia Stem Cells