Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research interests include Secretion, Chemistry, Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis, Mucus, and Cell biology.
Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine
A novel SLC26A9 inhibitor, S9-A13, reveals a minor contribution of SLC26A9 to constitutive airway chloride secretion
Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract
SLC26A9 in airways and intestine: secretion or absorption?
TMEM16A/F support exocytosis but do not inhibit Notch-mediated goblet cell metaplasia of BCi-NS1.1 human airway epithelium
KCNE1 does not shift TMEM16A from a Ca2+ dependent to a voltage dependent Cl- channel and is not expressed in renal proximal tubule
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease
The <scp>SLC26A9</scp> inhibitor <scp>S9‐A13</scp> provides no evidence for a role of <scp>SLC26A9</scp> in airway chloride secretion but suggests a contribution to regulation of <scp>ASL pH</scp> and gastric proton secretion
Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids
Expression of SLC26A9 in Airways and Its Potential Role in Asthma
Drug repurposing for Cystic Fibrosis: identification of drugs that induce CFTR-independent fluid secretion in nasal organoids
CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A
Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease
Calmodulin-Dependent Regulation of Overexpressed but Not Endogenous TMEM16A Expressed in Airway Epithelial Cells
Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A
TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells
Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption
Ca2+ Dependence of Volume-Regulated VRAC/LRRC8 and TMEM16A Cl– Channels
Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G
Assessment of Distinct Electrophysiological Parameters in Rectal Biopsies for the Choice of the Best Diagnosis/Prognosis Biomarkers for Cystic Fibrosis
Control of Ion Transport by Tmem16a Expressed in Murine Intestine