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Y. Grace Chen

Panyu District Central Hospital · US
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include RNA modifications and cancer, RNA Research and Splicing, Cancer-related molecular mechanisms research, and Circular RNAs in diseases.
h-index
14
citations
5,035
works
23
NIH funding
primary concept
email

Recent publications

Development of a monoclonal antibody-based time-resolved fluorescence immunochromatographic assay strip for rapid and quantitative determination of ubiquitin C-terminal hydrolase L1 in serum
Microchimica Acta 2026cited by 0position: middledoi
Inflammasome activation in infected macrophages drives COVID-19 pathology
Nature 2022cited by 523position: middledoi
Cellular origins of dsRNA, their recognition and consequences
Nature Reviews Molecular Cell Biology 2021cited by 427position: firstdoi
N6-Methyladenosine Modification Controls Circular RNA Immunity
Molecular Cell 2019cited by 575position: firstdoi
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
Cell 2018cited by 484position: middledoi
m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways
Nature 2017cited by 1,040position: middledoi
Sensing Self and Foreign Circular RNAs by Intron Identity
Molecular Cell 2017cited by 456position: firstdoi
Discovery and biological characterization of geranylated RNA in bacteria
Nature Chemical Biology 2012cited by 125position: middledoi

Grants

Collaborative Research: MFS-SPEED: D-Diameter - Data-Driven Innovation Advancing Macromolecular Engineering Towards Efficient Recycling
NSF2517827$1,250,0002025–2028PIRePORTER
Collaborative Research: High-Dimensional Tensor Learning under Labeled-Data Scarcity
NSF2412577$87,0262024–2027PIRePORTER
CAS: Lewis Pair Polymerization: Compounded Sequence and Spatiotemporal Controls for Precision Synthesis of Sustainable Linear and Cyclic Block Copolymers
NSF2305058$699,2542023–2027PIRePORTER
CAS: Diastereoselective Polymerization Catalysis for Stereo-Sequenced Polymers with Biodegradability and Chemical Circularity
NSF1955482$490,0002020–2024PIRePORTER
LARGE-SCALE ALL-ATOM SIMULATIONS OF NEUTRAL-SOLUTE TRANSPORTERS IN CELL-LIKE ENVIRONMENTS
NSF2031576$3,0002020–2023PIRePORTER
Lewis Pair Polymerization: Controlling Polymer Tacticity and Topology
NSF1904962$664,2502019–2023PIRePORTER
PostDoctoral Research Fellowship
NSF1803357$150,0002018–2022PIRePORTER
PostDoctoral Research Fellowship
NSF1803241$150,0002018–2022PIRePORTER
SusChEM: Stereoselective Polymerization Catalysis of Biomass Monomers by Chiral Transition-Metal and Organic Catalysts
NSF1664915$450,0002017–2020PIRePORTER
EAGER: Biomanufacturing: Large-Scale Isolation of T Cells with High-Performance Phenotype for Enhancing Adoptive T-Cell Therapy
NSF1645406$299,6112017–2018PIRePORTER
CAREER: Seeing in the Dark--Engineering Cytotoxic T Cells to Detect and Respond to Intracellular Cancer Markers
NSF1553767$516,2842016–2021PIRePORTER
I-Corps: Immune Profiling for Patient Stratification in Clinical Drug Development of Autoimmune and Cancer Biologic Therapies
NSF1647037$50,0002016–2018PIRePORTER
SusChEM: Lewis Pair Polymerization: A Powerful Synthetic Strategy for Sustainable and Functional Polymers
NSF1507702$540,0002015–2019PIRePORTER
AF: Small: Volumetric Alignment of Protein Cavities for the Analysis of Ligand Binding Specificity
NSF1320137$469,0002014–2017PIRePORTER
SusChEM: Stereoselective Polymerization of Biomass Monomers by Transition-Metal and Organic Catalysts
NSF1300267$447,0002013–2016PIRePORTER
Synthesis of Sustainable Polymers by Silylium-Catalyzed Polymerization of Renewable Feedstocks
NSF1150792$386,1272012–2015PIRePORTER
Asymmetric Coordination Polymerization Catalysis of Polar Vinyl Monomers
NSF1012326$420,0002010–2013PIRePORTER
Asymmetric Catalysis by Chiral-Polymer-Induced and Stabilized, Chiral-Surface Nanoclusters
NSF0756633$400,0002009–2012PIRePORTER
Living and Stereoselective Anionic Polymerization by Dinuclear Ambiphilic Silicon Propagators
NSF0848845$260,0002009–2012PIRePORTER
Diastereospecific Ion-Pairing Polymerization of Functionalized Vinyl Monomers
NSF0718061$448,0002007–2010PIRePORTER
Diastereospecific Ion-Pairing, "Amphicatalytic" Polymerization of Functionalized Vinyl Monomers
NSF0415270$384,0002004–2007PIRePORTER
SBIR Phase I: Casting Technology for High Temperature Titanium Alloy Lattice Block Structures
NSF0420252$100,0002004–2004PIRePORTER
STTR Phase I: Forming of Cast Titanium Structures by Transformation Superplasticity
NSF0420083$100,0002004–2005PIRePORTER
SBIR Phase I: Niobium Silicide Intermetallics Castings for the Next Generation of Very High Temperature Applications
NSF0128423$100,0002002–2002PIRePORTER
U.S.-China Cooperative Research: Fate and Transfer of Metals and PCB's In Baiyangdian Lake
NSF9911756$12,4002000–2002PIRePORTER

Frequent collaborators

Howard Y. Chang · Amgen (United States)4 papers (2017–2019)James P. Broughton · Mammoth Biosciences (United States)2 papers (2017–2019)Richard A. Flavell · University of California, San Francisco2 papers (2017–2022)Sun Hur · Boston Children's Hospital2 papers (2019–2021)Jun Zhao · Yunnan Academy of Agricultural Sciences2 papers (2017–2022)Akiko Iwasaki · Yale University2 papers (2017–2022)Jeewon Kim · Westmead Hospital2 papers (2018–2019)Pedro J. Batista · Stanford University2 papers (2017–2017)Yuval Kluger · Yale University2 papers (2017–2022)Maxwell R. Mumbach · Stanford University1 papers (2018–2018)Christina Curtis · Stanford University1 papers (2018–2018)Shu Zhu · University of Science and Technology of China1 papers (2017–2017)Bali Pulendran · Stanford University1 papers (2019–2019) · 1 papers (2018–2018)Jing He · University of Colorado Denver1 papers (2018–2018)Zhenye Zhan · Jinan University1 papers (2026–2026)Yiyun Chen · National Chung Hsing University1 papers (2012–2012) · 1 papers (2022–2022)Aaron M. Leconte · Scripps College1 papers (2012–2012)Jiyu Tong · Sichuan University1 papers (2017–2017)