Area of research
Molecular Biology · Immunology
Research interest
Research interests include Single-cell and spatial transcriptomics, Genomics and Chromatin Dynamics, Immune cells in cancer, and Gene expression and cancer classification.
RCDdb: A manually curated database and analysis platform for regulated cell death
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment
Landscape and significance of human super enhancer-driven core transcription regulatory circuitry
Novel insight into the underlying dysregulation mechanisms of immune cell-to-cell communication by analyzing multitissue single-cell atlas of two COVID-19 patients
SCInter: A comprehensive single-cell transcriptome integration database for human and mouse
Inflammasome activation in infected macrophages drives COVID-19 pathology
Zero-preserving imputation of single-cell RNA-seq data
SEdb 2.0: a comprehensive super-enhancer database of human and mouse
m <sup>6</sup> A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART
A humanized mouse model of chronic COVID-19
TcoFBase: a comprehensive database for decoding the regulatory transcription co-factors in human and mouse
TF-Marker: A comprehensive manually curated database for transcription factors and related markers in specific cell and tissue types in human.
Key factors determining competitions between double-stranded RNAs in Tribolium castaneum
TF-Marker: A comprehensive manually curated database for transcription factors and related markers in specific cell and tissue types in human.
An in vivo screen of noncoding loci reveals that <i>Daedalus</i> is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity
ATACdb: a comprehensive human chromatin accessibility database
The induction and function of the anti-inflammatory fate of TH17 cells
VARAdb: a comprehensive variation annotation database for human
Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection
A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies
Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function
KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells
The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression