Area of research
Oncology · Cancer Research
Research interest
Research interests include Cancer Cells and Metastasis, Cancer, Hypoxia, and Metabolism, Cellular Mechanics and Interactions, and Glioma Diagnosis and Treatment.
Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
Subpopulation targeting of pyruvate dehydrogenase and GLUT1 decouples metabolic heterogeneity during collective cancer cell invasion
Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning
Feeling Stress: The Mechanics of Cancer Progression and Aggression
α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site
Abstract C24: Interplay between ECM stiffness, miR-203 and mammographic density
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression
The extracellular matrix modulates the hallmarks of cancer
Extracellular matrix assembly: a multiscale deconstruction
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression