Area of research
Neurology · Oncology
Research interest
Research interests include Barrier Structure and Function Studies, Neuroinflammation and Neurodegeneration Mechanisms, Drug Transport and Resistance Mechanisms, and Neurogenesis and neuroplasticity mechanisms.
Dynamic fibroblast–immune interactions shape recovery after brain injury
Resolving the mysteries of brain clearance and immune surveillance
Regional heterogeneity of the blood-brain barrier
Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism
CD98hc is a target for brain delivery of biotherapeutics
Epsilon toxin–producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege
Specification of CNS macrophage subsets occurs postnatally in defined niches
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders
CNS fibroblasts form a fibrotic scar in response to immune cell infiltration
Emerging roles for CNS fibroblasts in health, injury and disease
Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation
The blood–brain barrier in health and disease: Important unanswered questions
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes
Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood–brain barrier dysfunction module
Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids
Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties
Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
Altered cargo proteins of human plasma endothelial cell–derived exosomes in atherosclerotic cerebrovascular disease
Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior
Oligodendrocyte precursors migrate along vasculature in the developing nervous system
Formation and maintenance of the BBB
LSR/angulin-1 is a tricellular tight junction protein involved in blood–brain barrier formation
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis
Experimental Cerebral Malaria Pathogenesis—Hemodynamics at the Blood Brain Barrier
Regulation of Intrinsic Axon Growth Ability at Retinal Ganglion Cell Growth Cones
Development, maintenance and disruption of the blood-brain barrier
Transporters of the blood–brain and blood–CSF interfaces in development and in the adult
‘Sealing off the CNS’: cellular and molecular regulation of blood–brain barriergenesis
Foxc1 is required by pericytes during fetal brain angiogenesis