Area of research
Biological Psychiatry · Behavioral Neuroscience
Research interest
Research interests include Tryptophan and brain disorders, Stress Responses and Cortisol, Schizophrenia research and treatment, and Bipolar Disorder and Treatment.
The role of proinflammatory response and the kynurenine pathway in the association between childhood maltreatment and lifetime substance use disorder
Kynurenic Acid and Promotion of Activity-Dependent Synapse Elimination in Schizophrenia
Cognitive Function and Variability in Antipsychotic Drug–Naive Patients With First-Episode Psychosis
Neuroactive Kynurenines as Pharmacological Targets: New Experimental Tools and Exciting Therapeutic Opportunities
Central and peripheral kynurenine pathway metabolites in COVID-19: Implications for neurological and immunological responses
The Tryptophan Metabolite Indole-3-Propionic Acid Raises Kynurenic Acid Levels in the Rat Brain In Vivo
Biological Factors Underpinning Suicidal Behaviour: An Update
Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression
Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression
Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia
Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia
Peripheral and central levels of kynurenic acid in bipolar disorder subjects and healthy controls
Epidemiological, genetic, and clinical characterization by age of newly diagnosed acute myeloid leukemia based on an academic population-based registry study (AMLSG BiO)
Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28
CSF GABA is reduced in first-episode psychosis and associates to symptom severity
The kynurenine pathway in schizophrenia and bipolar disorder
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation
Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans
Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients
Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders
Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes
Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia — significance for activation of the kynurenine pathway
The role of inflammation in suicidal behaviour
A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder
Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms
Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression
A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality
Imbalanced Kynurenine Pathway in Schizophrenia
Low <scp>IL</scp>‐8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels