Area of research
Molecular Biology · Hematology
Research interest
Research interests include RNA Research and Splicing, RNA modifications and cancer, Acute Myeloid Leukemia Research, and RNA and protein synthesis mechanisms.
Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias
Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms
Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
Short H2A histone variants are expressed in cancer
<i>ZBTB33</i> Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing
CD38 in Advanced Prostate Cancers
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms
Spliceosomal disruption of the non-canonical BAF complex in cancer
Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations
Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene <i>U2af1</i>
Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival
Integrative Clinical Genomics of Advanced Prostate Cancer
SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition
Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment
Massive Mitochondrial Gene Transfer in a Parasitic Flowering Plant Clade
Alternative Splicing of RNA Triplets Is Often Regulated and Accelerates Proteome Evolution
CSBR: Natural History: Development of a Liquid Nitrogen System for the Genetic Resources Collection, Natural Science Research Laboratory, Museum of Texas Tech University
TOMS - Teachers of Mathematics Scholarships
Collection Enhancement, Enlargement, and Compactorization at the Natural Science Research Laboratory
Enhancement of Collections and Safety at the Museum of Texas Tech University
Collaborative Research: Molecular, Biochemical and Quantitative Genetics of Glucosinolates and Myrosinase in Brassica
NSF Postdoctoral Research Fellowships in Plant Biology
Development of the Sense of Taste