Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include RNA Research and Splicing, RNA and protein synthesis mechanisms, RNA modifications and cancer, and Genomics and Chromatin Dynamics.
A splice-switching antisense oligonucleotide approach for pediatric genetic epilepsies
Widespread naturally variable human exons aid genetic interpretation
Molecular and cellular context influences SCN8A variant function
Regulatory features aid interpretation of 3′UTR variants
Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro
Widespread naturally variable human exons aid genetic interpretation
Sensory nerves enhance triple-negative breast cancer invasion and metastasis via the axon guidance molecule PlexinB3
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes
Widespread occurrence of hybrid internal-terminal exons in human transcriptomes
Author Correction: Perspectives on ENCODE
Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
Sensory nerves enhance triple-negative breast cancer migration and metastasis via the axon guidance molecule PlexinB3
Expanded encyclopaedias of DNA elements in the human and mouse genomes
A large-scale binding and functional map of human RNA-binding proteins
Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription
Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes
Exon-Mediated Activation of Transcription Starts
Widespread PERK-dependent repression of ER targets in response to ER stress
Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA
Sequence, Structure, and Context Preferences of Human RNA Binding Proteins
Transcriptome alterations in myotonic dystrophy skeletal muscle and heart
Widespread Accumulation of Ribosome-Associated Isolated 3′ UTRs in Neuronal Cell Populations of the Aging Brain
Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow
Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA
Widespread PERK-dependent repression of ER targets in response to ER stress
A Large-Scale Binding and Functional Map of Human RNA Binding Proteins
The kinetics of pre-mRNA splicing in the Drosophila genome and the influence of gene architecture