Area of research
Molecular Biology · Hematology
Research interest
Research interests include RNA Research and Splicing, RNA modifications and cancer, RNA and protein synthesis mechanisms, and Chronic Myeloid Leukemia Treatments.
Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted
Phenylpyrazoles as Inhibitors of the m<sup>6</sup>A RNA-Binding Protein YTHDF2
The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibition
Foxo1 regulates intestinal tissue–resident memory CD8 T cell biology in an anatomic compartment– and context-specific manner
LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis
Bento: a toolkit for subcellular analysis of spatial transcriptomics data
Steering research on mRNA splicing in cancer towards clinical translation
Decoding protein–RNA interactions using CLIP-based methodologies
Integrated multi-omics analysis of zinc-finger proteins uncovers roles in RNA regulation
Large-scale evaluation of the ability of RNA-binding proteins to activate exon inclusion
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies
A phage nucleus-associated RNA-binding protein is required for jumbo phage infection
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes
Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis
Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size
Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and remodeling
Proteomic discovery of chemical probes that perturb protein complexes in human cells
Remodeling oncogenic transcriptomes by small molecules targeting NONO
HydRA: Deep-learning models for predicting RNA-binding capacity from protein interaction association context and protein sequence
Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death
Skipper analysis of eCLIP datasets enables sensitive detection of constrained translation factor binding sites
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
Early transcriptional and epigenetic divergence of CD8+ T cells responding to acute versus chronic infection
Xiphoid nucleus of the midline thalamus controls cold-induced food seeking
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery
Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing
Illuminating RNA biology through imaging
An RNA-targeting CRISPR–Cas13d system alleviates disease-related phenotypes in Huntington’s disease models
Transcriptome-wide identification of RNA-binding protein binding sites using seCLIP-seq