Area of research
Neurology · Cancer Research
Research interest
Research interests include Biology, Cancer research, Neuroblastoma, microRNA, Gene, and Medicine.
Pathway for the Development of ATR Inhibitors in Pediatric Malignancies: An ACCELERATE Multistakeholder Analysis
RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition
Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma
The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis
A mechanistic classification of clinical phenotypes in neuroblastoma
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets
LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis
Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice
ALK positively regulates MYCN activity through repression of HBP1 expression
Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
MYCN and HDAC5 transcriptionally repress <i>CD9</i> to trigger invasion and metastasis in neuroblastoma
LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19
Mutational dynamics between primary and relapse neuroblastomas
Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition
Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment
LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia
MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
miR‐542‐3p exerts tumor suppressive functions in neuroblastoma by downregulating <scp>S</scp> urvivin
Refinement of the critical 2p25.3 deletion region: the role of MYT1L in intellectual disability and obesity
MYCN-targeting miRNAs are predominantly downregulated during MYCN-driven neuroblastoma tumor formation
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
CASP8 SNP D302H (rs1045485) Is Associated with Worse Survival in MYCN-Amplified Neuroblastoma Patients
Abstract 3967: BET protein inhibitor OTX015 has selective anti-tumoral activity in preclinical models of MYCN- amplified neuroblastoma
Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia
Histone Chaperone CHAF1A Inhibits Differentiation and Promotes Aggressive Neuroblastoma
Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes