Area of research
Oncology · Cancer Research
Research interest
Research interests include Biology, Colorectal cancer, Cancer research, Medicine, Cancer stem cell, and Metastasis.
MACC1 Regulates LGR5 to Promote Cancer Stem Cell Properties in Colorectal Cancer
Photon and Proton irradiation in Patient-derived, Three-Dimensional Soft Tissue Sarcoma Models
Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis
RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models
RNA-Sequencing of Long-Term Label-Retaining Colon Cancer Stem Cells Identifies Novel Regulators of Quiescence
Identification of a Nervous System Gene Expression Signature in Colon Cancer Stem Cells Reveals a Role for Neural Crest Regulators <i>EGR2</i> and <i>SOX2</i> in Tumorigenesis
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
Reflection of neuroblastoma intratumor heterogeneity in the new OHC‐NB1 disease model
Abstract 4525: Modulating chemoresistance: Uncovering the role of mutant SMAD4<sup>R361H</sup>in colorectal cancer using PDO and PDX models
From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity
Abstract 4099: Novel patient-derived 3D (PD3D) cell models and matched patient-derived xenografts (PDX) from peritoneal metastasis of colorectal cancer for drug testing and biomarker analysis
Abstract 5013: Rapid generation of phenomic and functional profiles of patient-derived 3D cell culture models for identification of treatment vulnerabilities of breast cancer: Early results of the EFRE-PoP project
Successful generation of patient derived xenografts and patient derived 3D cultures as preclinical models for breast cancer.
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells
The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells
In Vitro Three-Dimensional Cell Cultures as Tool for Precision Medicine
Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures
Abstract 2412: Reconstructing intratumor heterogeneity: lessons from therapeutic intervention in patient-specific models
Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes
A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells