Area of research
Oncology · Cancer Research
Research interest
Research interests include Cancer-related Molecular Pathways, Cancer Genomics and Diagnostics, Colorectal Cancer Treatments and Studies, and Cancer Cells and Metastasis.
A diagnostic challenge of KIT p.V559D and BRAF p.G469A mutations in a paragastric mass
Tumour mutational burden and survival with molecularly matched therapy
The <scp>FGFR</scp> inhibitor <scp>PD173074</scp> binds to the C‐terminus of oncofetal <scp>HMGA2</scp> and modulates its <scp>DNA</scp> ‐binding and transcriptional activation functions
Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis
IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation
Evaluation of JQ1 Combined With Docetaxel for the Treatment of Prostate Cancer Cells in 2D- and 3D-Culture Systems
Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL
Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study
RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence
Generation of Patient-Derived Colorectal Cancer Organoids for RAS Studies
Rapid testing of candidate oncogenes and tumour suppressor genes in signal transduction and neoplastic transformation
RNA-Sequencing of Long-Term Label-Retaining Colon Cancer Stem Cells Identifies Novel Regulators of Quiescence
Identification of a Nervous System Gene Expression Signature in Colon Cancer Stem Cells Reveals a Role for Neural Crest Regulators <i>EGR2</i> and <i>SOX2</i> in Tumorigenesis
Support of a molecular tumour board by an evidence-based decision management system for precision oncology
SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
Mutation-specific effects of NRAS oncogenes in colorectal cancer cells
Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
Comparative Analysis of Public Knowledge Bases for Precision Oncology
Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer
VIST - a Variant-Information Search Tool for precision oncology
Clinical impact of comprehensive versus targeted genomic analysis for precision oncology.
Abstract 4525: Modulating chemoresistance: Uncovering the role of mutant SMAD4<sup>R361H</sup>in colorectal cancer using PDO and PDX models
Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer
Efficacy of a structured workflow for the interpretation of comprehensive genomic analysis data in clinical routine.
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells
DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer
The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells