Area of research
Electrical and Electronic Engineering · Immunology
Research interest
Research interests include Molecular Junctions and Nanostructures, Immunotherapy and Immune Responses, CAR-T cell therapy research, and Nanowire Synthesis and Applications.
Disease diagnostics using machine learning of B cell and T cell receptor sequences
Long COVID trajectories in the prospectively followed RECOVER-Adult US cohort
Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities
Additional file 2 of Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Multiple early factors anticipate post-acute COVID-19 sequelae
Non-viral precision T cell receptor replacement for personalized cell therapy
KIR <sup>+</sup> CD8 <sup>+</sup> T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
Studying severe long COVID to understand post-infectious disorders beyond COVID-19
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency
Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression
Prediction of HLA genotypes from single-cell transcriptome data
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19
Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19
Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19
Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line
Unique challenges for glioblastoma immunotherapy—discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank
T cell antigen discovery via trogocytosis
Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial
T cell antigen discovery via signaling and antigen-presenting bifunctional receptors
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer