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David Baltimore

California Institute of Technology · US
🔎 Find collaborators in Immunology · Genetics →
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Area of research
Immunology · Genetics
Research interest
Research interests include Virus-based gene therapy research, Viral Infections and Immunology Research, Immune Cell Function and Interaction, and T-cell and B-cell Immunology.
h-index
210
citations
172,969
works
1,142
NIH funding
primary concept
email

Recent publications

NF-κB: master regulator of cellular responses in health and disease
Immunity & Inflammation 2025cited by 40position: lastdoi
Non-viral precision T cell receptor replacement for personalized cell therapy
Nature 2022cited by 269position: middledoi
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line
Nature Communications 2020cited by 103position: middledoi
Alternative mRNA splicing in cancer immunotherapy
Nature reviews. Immunology 2019cited by 270position: middledoi
T cell antigen discovery via trogocytosis
Nature Methods 2019cited by 160position: lastdoi
T cell antigen discovery via signaling and antigen-presenting bifunctional receptors
Nature Methods 2019cited by 153position: lastdoi
The Cellular Immunotherapy Revolution: Arming the Immune System for Precision Therapy
Trends in Immunology 2019cited by 101position: middledoi
Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood
Cell Reports 2019cited by 80position: middledoi
Dual mechanisms of posttranscriptional regulation of Tet2 by Let-7 microRNA in macrophages
Proceedings of the National Academy of Sciences 2019cited by 67position: lastdoi
Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age
Cell Reports 2018cited by 194position: lastdoi
Let-7 Suppresses B Cell Activation through Restricting the Availability of Necessary Nutrients
Cell Metabolism 2018cited by 95position: lastdoi
Isolation and characterization of NY-ESO-1–specific T cell receptors restricted on various MHC molecules
Proceedings of the National Academy of Sciences 2018cited by 71position: lastdoi
Author Correction: An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
Nature Communications 2018cited by 15position: lastdoi
Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
Cell 2017cited by 283position: middledoi
Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids
Nature Methods 2017cited by 265position: middledoi
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
Nature Communications 2017cited by 258position: lastdoi
Human Embryo Editing: Opportunities and Importance of Transnational Cooperation
Cell stem cell 2017cited by 20position: lastdoi
Photon‐Induced Near‐Field Electron Microscopy of Eukaryotic Cells
Angewandte Chemie International Edition 2017cited by 18position: middledoi
Photon‐Induced Near‐Field Electron Microscopy of Eukaryotic Cells
Angewandte Chemie 2017cited by 3position: middledoi
Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1
Journal of Biological Chemistry 2016cited by 93position: middledoi
Domain-swapped T cell receptors improve the safety of TCR gene therapy
eLife 2016cited by 65position: lastdoi
A path toward understanding neurodegeneration
Science 2016cited by 11position: lastdoi
A prudent path forward for genomic engineering and germline gene modification
Science 2015cited by 698position: firstdoi
The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression
Immunity 2015cited by 97position: lastdoi
The microRNA-212/132 cluster regulates B cell development by targeting Sox4
The Journal of Experimental Medicine 2015cited by 70position: lastdoi
The role of microRNA in nutritional control
Journal of Internal Medicine 2015cited by 44position: lastdoi
Single-molecule analysis of RAG-mediated V(D)J DNA cleavage
Proceedings of the National Academy of Sciences 2015cited by 23position: middledoi
Heme-Mediated SPI-C Induction Promotes Monocyte Differentiation into Iron-Recycling Macrophages
Cell 2014cited by 411position: middledoi
Conversion of Danger Signals into Cytokine Signals by Hematopoietic Stem and Progenitor Cells for Regulation of Stress-Induced Hematopoiesis
Cell stem cell 2014cited by 333position: lastdoi
Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma
Clinical Cancer Research 2014cited by 251position: middledoi

Grants

Institute Wide Integration of Computer Based Instructional Aids into the Science and Technology Curriculum at Caltech
NSF9652066$200,0001996–2000PIRePORTER
ARFMP: Relocation and Renovation of Protein Sequencing and Biopolymer Facilities
NSF9021776$275,0001991–1992PIRePORTER

Frequent collaborators

Jimmy L. Zhao · Memorial Sloan Kettering Cancer Center11 papers (2012–2018)Antoni Ribas · UCLA Medical Center7 papers (2013–2020)Arnav Mehta · Massachusetts General Hospital7 papers (2012–2018)Michael T. Bethune · California Institute of Technology7 papers (2016–2019)James R. Heath · Sandia National Laboratories7 papers (2013–2020)Ryan M. O’Connell · University of Utah7 papers (2012–2014)Dinesh S. Rao · University of California, Los Angeles6 papers (2012–2014)Mati Mann · California Institute of Technology5 papers (2015–2018)Owen N. Witte · University of California, Los Angeles5 papers (2013–2019)Guideng Li · Center for Systems Biology5 papers (2019–2020)Yvette Garcia Flores · California Institute of Technology4 papers (2013–2018)Stephanie Wong · California Institute of Technology4 papers (2018–2020)Donghui Cheng · University of Electronic Science and Technology of China4 papers (2016–2019)Georgi K. Marinov · California Institute of Technology4 papers (2015–2018)Eric H. Gschweng · Research Institute of Dallas3 papers (2013–2017)Donald B. Kohn · University of California, Berkeley3 papers (2013–2017)Songming Peng · Sunesis (United States)3 papers (2019–2019)Alejandro B. Balazs · Ragon Institute of MGH, MIT and Harvard3 papers (2013–2014)Yapeng Su · California Institute of Technology3 papers (2019–2020)Jesse M. Zaretsky · University of California, Los Angeles3 papers (2019–2019)
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