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Arnav Mehta

Massachusetts General Hospital · US
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Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Gastric Cancer Management and Outcomes, Gastrointestinal Tumor Research and Treatment, and Helicobacter pylori-related gastroenterology studies.
h-index
32
citations
5,916
works
275
NIH funding
primary concept
email

Recent publications

Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants
Cell Reports Medicine 2025cited by 9position: middledoi
Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics
eLife 2025cited by 4position: middledoi
Transcriptomic Plasticity Is a Hallmark of Metastatic Pancreatic Cancer
Cancer Research 2025cited by 1position: middledoi
Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics
eLife 2025cited by 1position: middledoi
Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy
Nature Immunology 2024cited by 123position: middledoi
Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial
Nature Medicine 2023cited by 181position: middledoi
Targeting TBK1 to overcome resistance to cancer immunotherapy
Nature 2023cited by 165position: middledoi
Association of Somatic <scp><i>TET2</i></scp> Mutations With Giant Cell Arteritis
Arthritis & Rheumatology 2023cited by 24position: middledoi
Development of an artificial intelligence-derived histologic signature associated with adjuvant gemcitabine treatment outcomes in pancreatic cancer
Cell Reports Medicine 2023cited by 19position: middledoi
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
Nature Genetics 2022cited by 397position: middledoi
Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients
Cell Reports Medicine 2022cited by 70position: middledoi
Inferring gene regulation from stochastic transcriptional variation across single cells at steady state
Proceedings of the National Academy of Sciences 2022cited by 57position: middledoi
Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions
Cell Reports Medicine 2021cited by 309position: middledoi
Radiation therapy enhances immunotherapy response in microsatellite stable colorectal and pancreatic adenocarcinoma in a phase II trial
Nature Cancer 2021cited by 282position: middledoi
SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes
Journal of Clinical Investigation 2021cited by 122position: middledoi
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro
Science Translational Medicine 2021cited by 102position: middledoi
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
CA A Cancer Journal for Clinicians 2020cited by 513position: middledoi
Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome
Science Advances 2020cited by 59position: middledoi
Fitness Landscape of Clonal Hematopoiesis Under Selective Pressure of Immune Checkpoint Blockade
JCO Precision Oncology 2020cited by 43position: middledoi
Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age
Cell Reports 2018cited by 194position: middledoi
Immunotherapy Resistance by Inflammation-Induced Dedifferentiation
Cancer Discovery 2018cited by 182position: firstdoi
Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma
Neuro-Oncology 2018cited by 96position: middledoi
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment
eLife 2018cited by 87position: middledoi
Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo
Neuro-Oncology 2018cited by 22position: middledoi
Author Correction: An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
Nature Communications 2018cited by 15position: middledoi
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
Nature Communications 2017cited by 258position: middledoi
The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression
Immunity 2015cited by 97position: firstdoi
The microRNA-212/132 cluster regulates B cell development by targeting Sox4
The Journal of Experimental Medicine 2015cited by 70position: firstdoi
Conversion of Danger Signals into Cytokine Signals by Hematopoietic Stem and Progenitor Cells for Regulation of Stress-Induced Hematopoiesis
Cell stem cell 2014cited by 333position: middledoi
Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A
Proceedings of the National Academy of Sciences 2012cited by 149position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

David Baltimore · California Institute of Technology7 papers (2012–2018)Jimmy L. Zhao · Memorial Sloan Kettering Cancer Center5 papers (2014–2018)Mati Mann · California Institute of Technology5 papers (2015–2018)Georgi K. Marinov · California Institute of Technology4 papers (2015–2018)Yvette Garcia Flores · California Institute of Technology3 papers (2015–2018)Kevin Lee · California Institute of Technology3 papers (2017–2018) · 2 papers (2015–2018)Aviv Regev · Moscow Institute of Thermal Technology2 papers (2015–2018)Genevieve M. Boland · Harvard University2 papers (2020–2020) · 2 papers (2015–2015)Li‐Fan Lu · University of California San Diego2 papers (2017–2018)Xiaomi Du · California Institute of Technology2 papers (2015–2015)Alexander Y. Rudensky · Rockefeller University2 papers (2017–2018)Ryan M. O’Connell · University of Utah2 papers (2012–2014)Dennie T. Frederick · Broad Institute2 papers (2020–2020)Nir Hacohen · Broad Institute2 papers (2020–2021)Christopher J. Gibson · Merck & Co., Inc., Rahway, NJ, USA (United States)2 papers (2020–2023)Nikita Sinha · University of North Carolina at Chapel Hill2 papers (2012–2015)Benjamin L. Ebert · Harvard University2 papers (2020–2023)Kamal Chowdhury · University of California, Santa Barbara2 papers (2015–2015)
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