Area of research
Pathology and Forensic Medicine · Physiology
Research interest
Research interests include Spinal Cord Injury Research, Pain Mechanisms and Treatments, Nerve injury and regeneration, and Amyotrophic Lateral Sclerosis Research.
Long-term clinical and safety outcomes from a single-site phase 1 study of neural stem cell transplantation for chronic thoracic spinal cord injury
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation
Expandable Sendai-Virus-Reprogrammed Human iPSC-Neuronal Precursors: <i>In Vivo</i> Post-Grafting Safety Characterization in Rats and Adult Pig
Precision spinal gene delivery-induced functional switch in nociceptive neurons reverses neuropathic pain
Biomimetic 3D-printed scaffolds for spinal cord injury repair
Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
Selective Formation of Porous Pt Nanorods for Highly Electrochemically Efficient Neural Electrode Interfaces
A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors
Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats
A First-in-Human, Phase I Study of Neural Stem Cell Transplantation for Chronic Spinal Cord Injury
ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
Survival of syngeneic and allogeneic iPSC–derived neural precursors after spinal grafting in minipigs
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs)
Macrophage Migration Inhibitory Factor as a Chaperone Inhibiting Accumulation of Misfolded SOD1
Large animal and primate models of spinal cord injury for the testing of novel therapies
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
A Transgenic Minipig Model of Huntington's Disease
Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation
Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury
Elevated PGC-1α Activity Sustains Mitochondrial Biogenesis and Muscle Function without Extending Survival in a Mouse Model of Inherited ALS
Human Neural Stem Cell Replacement Therapy for Amyotrophic Lateral Sclerosis by Spinal Transplantation
Survival and Differentiation of Human Embryonic Stem Cell-Derived Neural Precursors Grafted Spinally in Spinal Ischemia-Injured Rats or in Naive Immunosuppressed Minipigs: A Qualitative and Quantitative Study