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Leen Rigouts

London School of Hygiene & Tropical Medicine · GB
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Area of research
Infectious Diseases · Epidemiology
Research interest
Research interests include Tuberculosis, Mycobacterium tuberculosis, Medicine, Biology, Drug resistance, and Rifampicin.
h-index
citations
2,625
works
24
NIH funding
primary concept
email

Recent publications

Multicentre field evaluation of Xpert MTB/XDR in sub-Saharan Africa
ERJ Open Research 2025cited by 2position: lastdoi
Newly Identified <i>Mycobacterium africanum</i> Lineage 10, Central Africa
Emerging infectious diseases 2024cited by 48position: middledoi
Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study
The Lancet Microbe 2023cited by 99position: middledoi
Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment
European Respiratory Journal 2022cited by 35position: middledoi
Spot specimen testing with GeneXpert MTB/RIF results compared to morning specimen in a programmatic setting in Cotonou, Benin
BMC Infectious Diseases 2021cited by 3position: middledoi
A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region
Nature Communications 2020cited by 221position: middledoi
Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs
European Respiratory Journal 2020cited by 106position: middledoi
Prevalence and drivers of false-positive rifampicin-resistant Xpert MTB/RIF results: a prospective observational study in Rwanda
The Lancet Microbe 2020cited by 63position: middledoi
Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension
Tuberculosis 2020cited by 27position: middledoi
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues
Nature Reviews Microbiology 2019cited by 423position: middledoi
GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions
Nature Communications 2019cited by 199position: middledoi
Reference set of Mycobacterium tuberculosis clinical strains: A tool for research and product development
PLoS ONE 2019cited by 92position: middledoi
Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance
Scientific Reports 2019cited by 56position: middledoi
Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance study
The Lancet Infectious Diseases 2018cited by 160position: middledoi
Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase
Scientific Reports 2018cited by 101position: middledoi
A standardised method for interpreting the association between mutations and phenotypic drug resistance in<i>Mycobacterium tuberculosis</i>
European Respiratory Journal 2017cited by 332position: middledoi
How should discordance between molecular and growth-based assays for rifampicin resistance be investigated?
The International Journal of Tuberculosis and Lung Disease 2017cited by 36position: middledoi
Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project
The Lancet Infectious Diseases 2016cited by 165position: middledoi
Genetic Determinants of Drug Resistance in <i>Mycobacterium tuberculosis</i> and Their Diagnostic Value
American Journal of Respiratory and Critical Care Medicine 2016cited by 157position: middledoi
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance
BMC Medicine 2016cited by 113position: middledoi
Correlation of different phenotypic drug susceptibility testing methods for four fluoroquinolones in<i>Mycobacterium tuberculosis</i>
Journal of Antimicrobial Chemotherapy 2016cited by 34position: lastdoi
Specific<i>gyrA</i>gene mutations predict poor treatment outcome in MDR-TB
Journal of Antimicrobial Chemotherapy 2015cited by 95position: firstdoi
Bedaquiline susceptibility testing of <i>Mycobacterium tuberculosis</i> in an automated liquid culture system
Journal of Antimicrobial Chemotherapy 2015cited by 48position: lastdoi
Shifts in Mycobacterial Populations and Emerging Drug-Resistance in West and Central Africa
PLoS ONE 2014cited by 10position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Bouke C. de Jong · London School of Hygiene & Tropical Medicine13 papers (2014–2024)Armand Van Deun · Liverpool School of Tropical Medicine5 papers (2015–2020)Conor J. Meehan · University of Birmingham5 papers (2015–2020) · 5 papers (2014–2021)Philip Supply · London School of Hygiene & Tropical Medicine4 papers (2020–2024) · 4 papers (2014–2020) · 4 papers (2016–2020)Nele Coeck · University of Antwerp4 papers (2015–2016)Gabriela Torrea · Liverpool School of Tropical Medicine3 papers (2015–2020)Sébastien Gagneux · Swiss Tropical and Public Health Institute3 papers (2019–2023)Cyril Gaudin · London School of Hygiene & Tropical Medicine3 papers (2020–2024)Emmanuel André · European Union3 papers (2019–2020) · 2 papers (2019–2020)Daniela Brites · University of Georgia2 papers (2019–2020) · 2 papers (2015–2020)Taane G. Clark · London School of Hygiene & Tropical Medicine2 papers (2016–2024) · 2 papers (2020–2020)Maha Farhat · Harvard University2 papers (2016–2019)Jody Phelan · London School of Hygiene & Tropical Medicine2 papers (2016–2024)Stefan Niemann · University Hospital of Bern2 papers (2019–2020)
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