Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, RNA Research and Splicing, and Genomics and Chromatin Dynamics.
Single-molecule live-cell RNA imaging with CRISPR–Csm
CRISPRi-ART enables functional genomics of diverse bacteriophages using RNA-binding dCas13d
Precise transcript targeting by CRISPR-Csm complexes
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes
CasPEDIA Database: A Functional Classification System for Class 2 CRISPR-Cas Enzymes
Decorating chromatin for enhanced genome editing using CRISPR-Cas9
Xist Deletional Analysis Reveals an Interdependency between Xist RNA and Polycomb Complexes for Spreading along the Inactive X
Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome
Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1)
Genome-wide identification of autosomal genes with allelic imbalance of chromatin state
A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes
Locus-Specific Targeting to the X Chromosome Revealed by the RNA Interactome of CTCF
Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome
Long Noncoding RNAs: Past, Present, and Future
Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay