Area of research
Molecular Biology · Aging
Research interest
Research interests include Epigenetics and DNA Methylation, RNA modifications and cancer, Genetics, Aging, and Longevity in Model Organisms, and Genomics and Chromatin Dynamics.
WSTF nuclear autophagy regulates chronic but not acute inflammation
Human antibody targeting <i>Vibrio cholerae</i> O1 O-specific polysaccharide induces an amotile hypovirulent bacterial phenotype: mechanism of protection against cholera
Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease
Pitavastatin, Procollagen Pathways, and Plaque Stabilization in Patients With HIV
Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells
NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils
H3K36 methylation maintains cell identity by regulating opposing lineage programmes
A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis
Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma
Microbial modulation via cross-fostering prevents the effects of pervasive environmental stressors on microglia and social behavior, but not the dopamine system
Brain motor and fear circuits regulate leukocytes during acute stress
Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation
An intranasal ASO therapeutic targeting SARS-CoV-2
Sleep exerts lasting effects on hematopoietic stem cell function and diversity
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity
Nuclear autophagy interactome unveils WSTF as a constitutive nuclear inhibitor of inflammation
DEPCOD: a tool to detect and visualize co-evolution of protein domains
Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease
Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease
A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction
A MicroRNA Linking Human Positive Selection and Metabolic Disorders
A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells
S-phase Enriched Non-coding RNAs Regulate Gene Expression and Cell Cycle Progression
TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer’s Disease
Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes
The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing
Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition
The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF