Area of research
Geriatrics and Gerontology · Molecular Biology
Research interest
Research interests include Sirtuins and Resveratrol in Medicine, Epigenetics and DNA Methylation, Autophagy in Disease and Therapy, and Adipose Tissue and Metabolism.
A SIRT5-induced metabolic switch underlies chemoresistance and ATR checkpoint dependence in triple-negative breast cancer
Oxidation of retromer complex controls mitochondrial translation
Oxidation of retromer complex controls mitochondrial translation.
Editorial: Current insights in Epigenetics and Epigenomics
ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndrome.
SIRT2 attenuates stress-induced skeletal muscle atrophy by inhibiting glucocorticoid receptor signalling
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity.
The glutathione S-transferase Gstt1 drives survival and dissemination in metastases.
Loss of epigenetic information as a cause of mammalian aging
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
SIRT6 is a key regulator of mitochondrial function in the brain.
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Liquid biopsy reveals collateral tissue damage in cancer
DNA repair as a shared hallmark in cancer and ageing.
Liquid biopsy reveals collateral tissue damage in cancer.
Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling.
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine.
SIRT6 is a key regulator of mitochondrial function in the brain
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma.
Long-term analysis of antibodies elicited by SPUTNIK V: A prospective cohort study in Tucumán, Argentina
TiPpIng the balance in histone acetylation.
Nuclear metabolism and the regulation of the epigenome.
NR4A1 suppresses cancer replication stress through R-loop-dependent inhibition of immediate early gene transcriptional elongation
Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing
Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b