Area of research
Molecular Biology · Oncology
Research interest
Research interests include RNA modifications and cancer, Cancer Cells and Metastasis, Cancer Genomics and Diagnostics, and Melanoma and MAPK Pathways.
Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of <i>BRCA2</i> mutation carriers
The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis
Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy
AR Expression in Breast Cancer CTCs Associates with Bone Metastases
Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination
E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression
HER2 expression identifies dynamic functional states within circulating breast cancer cells
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b
Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition
Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer
The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer
Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment
MAPK7 Regulates EMT Features and Modulates the Generation of CTCs
The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
Patient-derived models of acquired resistance can identify effective drug combinations for cancer
Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
Isolation and Molecular Characterization of Circulating Melanoma Cells
Bioengineered Implantable Scaffolds as a Tool to Study Stromal-Derived Factors in Metastatic Cancer Models
Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition