Area of research
Cancer Research · Oncology
Research interest
Research interests include Cancer Cells and Metastasis, Cancer Genomics and Diagnostics, Cancer, Lipids, and Metabolism, and RNA modifications and cancer.
Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade
Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells
Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
HIF1A signaling selectively supports proliferation of breast cancer in the brain
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis
Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer
Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy
A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer
AR Expression in Breast Cancer CTCs Associates with Bone Metastases
Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination
HER2 expression identifies dynamic functional states within circulating breast cancer cells
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer
MAPK7 Regulates EMT Features and Modulates the Generation of CTCs
The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility
Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells
Isolation and Molecular Characterization of Circulating Melanoma Cells
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis