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Mehmet Toner

Shriners Hospitals for Children - Erie ·
Area of research
Biomedical Engineering · Oncology
Research interest
Research interests include 3D Printing in Biomedical Research, Microfluidic and Bio-sensing Technologies, Cancer Cells and Metastasis, and Cancer Genomics and Diagnostics.
h-index
122
citations
65,580
works
795
NIH funding
primary concept
email

Recent publications

Circulating tumor cells: Blood-based detection, molecular biology, and clinical applications
Cancer Cell 2025cited by 39position: middledoi
Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product
Nature Communications 2025cited by 31position: lastdoi
VCA supercooling in a swine partial hindlimb model
Scientific Reports 2024cited by 18position: middledoi
Circulating and Imaging Biomarkers of Radium-223 Response in Metastatic Castration-Resistant Prostate Cancer
JCO Precision Oncology 2024cited by 7position: middledoi
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
Cell 2023cited by 70position: middledoi
Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine
Proceedings of the National Academy of Sciences 2023cited by 43position: middledoi
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade
npj Precision Oncology 2023cited by 16position: middledoi
Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells
Breast Cancer Research and Treatment 2023cited by 4position: middledoi
Isolation of circulating tumor cells
iScience 2022cited by 64position: lastdoi
Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody
Proceedings of the National Academy of Sciences 2022cited by 21position: middledoi
Negative-Selection Enrichment of Circulating Tumor Cells from Peripheral Blood Using the Microfluidic CTC-iChip
Methods in molecular biology 2022cited by 13position: middledoi
Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition
Cancer Research 2022cited by 4position: middledoi
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
Molecular Cell 2021cited by 69position: middledoi
Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA
Breast Cancer Research and Treatment 2021cited by 16position: middledoi
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
Science 2020cited by 373position: middledoi
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
Cancer Discovery 2020cited by 225position: middledoi
Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells
Proceedings of the National Academy of Sciences 2020cited by 168position: lastdoi
HIF1A signaling selectively supports proliferation of breast cancer in the brain
Nature Communications 2020cited by 103position: middledoi
Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes
Lab on a Chip 2020cited by 76position: lastdoi
In-flow measurement of cell–cell adhesion using oscillatory inertial microfluidics
Lab on a Chip 2020cited by 23position: lastdoi
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis
Proceedings of the National Academy of Sciences 2019cited by 48position: middledoi
Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer
npj Precision Oncology 2019cited by 30position: middledoi
Quantitative Analysis of Circulating Tumor Cells Using RNA-Based Digital Scoring
Recent results in cancer research/Recent Results in Cancer Research 2019cited by 4position: middledoi
Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
Nature Communications 2018cited by 327position: middledoi
Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts
Cancer Discovery 2018cited by 215position: middledoi
An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer
Cancer Discovery 2018cited by 140position: middledoi
Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy
Proceedings of the National Academy of Sciences 2018cited by 130position: middledoi
A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer
Cancer Discovery 2018cited by 115position: middledoi
AR Expression in Breast Cancer CTCs Associates with Bone Metastases
Molecular Cancer Research 2018cited by 109position: middledoi
Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease
Gastroenterology 2018cited by 36position: middledoi

Grants

US-Turkey Cooperative Research: Cryopreservation of Starfish Oocytes, Eggs, and Embryos
NSF9907387$35,0001999–2002PIRePORTER

Frequent collaborators

Daniel A. Haber · Rambam Health Care Campus52 papers (2012–2025)Shyamala Maheswaran · Harvard University52 papers (2012–2025)Shannon L. Stott · Broad Institute26 papers (2012–2022)David T. Ting · Harvard University23 papers (2012–2022)Ben S. Wittner · Harvard University23 papers (2012–2023)Ravi Kapur · Biocon (India)17 papers (2014–2022)Lecia V. Sequist · Harvard University16 papers (2012–2018)Sridhar Ramaswamy · Harvard University15 papers (2012–2019)David T. Miyamoto · Harvard University14 papers (2012–2024)Aditya Bardia · Comprehensive Blood & Cancer Center12 papers (2013–2023)Nicola Aceto · ETH Zurich10 papers (2014–2021)Min Yu · University of Maryland, Baltimore9 papers (2012–2017)Taronish D. Dubash · Harvard University8 papers (2018–2023)Jon F. · Center for Cancer Research8 papers (2012–2022)Toshi Shioda · Center for Cancer Research7 papers (2014–2019)Joseph A. LiCausi · Center for Cancer Research7 papers (2016–2023)Keith H.K. Wong · Massachusetts General Hospital6 papers (2016–2018)Valentine Comaills · Center for Cancer Research6 papers (2014–2022)Yu Zheng · Yibin University6 papers (2015–2022)Rushil Desai · Harvard University6 papers (2014–2017)