Area of research
Oncology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Cancer Cells and Metastasis, DNA Repair Mechanisms, and Cancer Treatment and Pharmacology.
Macrovascular tumor infiltration and circulating tumor cell cluster dynamics in patients with cancer approaching the end of life
Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation
Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
Neutrophils escort circulating tumour cells to enable cell cycle progression
E-cadherin is required for metastasis in multiple models of breast cancer
Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding
AR Expression in Breast Cancer CTCs Associates with Bone Metastases
Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination
Microfluidic isolation of platelet-covered circulating tumor cells
SHP2 regulates proliferation and tumorigenicity of glioma stem cells
Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition
A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
En Route to Metastasis: Circulating Tumor Cell Clusters and Epithelial-to-Mesenchymal Transition
Tunable Nanostructured Coating for the Capture and Selective Release of Viable Circulating Tumor Cells
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility
Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells
Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop