Area of research
Cancer Research · Cell Biology
Research interest
Research interests include Biochemistry, Chemistry, Pentose phosphate pathway, Biology, Glycolysis, and Microglia.
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples
Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy
Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes
Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells
Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth
Oxidative pentose phosphate pathway and glucose anaplerosis support maintenance of mitochondrial <scp>NADPH</scp> pool under mitochondrial oxidative stress
Glyceraldehyde 3‐phosphate dehydrogenase modulates nonoxidative pentose phosphate pathway to provide anabolic precursors in hypoxic tumor cells
Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis