Area of research
Molecular Biology
Research interest
Research interests include Fungal and yeast genetics research, Genomics and Chromatin Dynamics, RNA and protein synthesis mechanisms, and RNA Research and Splicing.
Activity-dependent synapse elimination requires caspase-3 activation
Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking
Looking back and looking forward at Janelia
Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates
Dynamical localization of a thylakoid membrane binding protein is required for acquisition of photosynthetic competency
An RpaA-Dependent Sigma Factor Cascade Sets the Timing of Circadian Transcriptional Rhythms in Synechococcus elongatus
Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian output pathway
Cyanobacteria Maintain Constant Protein Concentration despite Genome Copy-Number Variation
Inference and Evolutionary Analysis of Genome-Scale Regulatory Networks in Large Phylogenies
ppGpp Controls Global Gene Expression in Light and in Darkness in S. elongatus
A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae
Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria
Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway
An Unstable Singularity Underlies Stochastic Phasing of the Circadian Clock in Individual Cyanobacterial Cells
The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine
Encoding four gene expression programs in the activation dynamics of a single transcription factor
A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution
Limits on information transduction through amplitude and frequency regulation of transcription factor activity
High-throughput microfluidics to control and measure signaling dynamics in single yeast cells
cis Determinants of Promoter Threshold and Activation Timescale
Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast
An Integrated Approach Reveals Regulatory Controls on Bacterial Translation Elongation
Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance
Circadian Control of Global Gene Expression by the Cyanobacterial Master Regulator RpaA
Promoter decoding of transcription factor dynamics involves a trade‐off between noise and control of gene expression
Two Antagonistic Clock-Regulated Histidine Kinases Time the Activation of Circadian Gene Expression
A serine sensor for multicellularity in a bacterium
The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment
Genome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe