← back to search

Julien Lescar

Nanyang Technological University · SG
Area of research
Public Health, Environmental and Occupational Health · Virology
Research interest
Research interests include Biology, Virology, Allosteric regulation, Dengue virus, Viral replication, and NS3.
h-index
citations
1,514
works
17
NIH funding
primary concept
email

Recent publications

Defining neutralization and allostery by antibodies against COVID-19 variants
Nature Communications 2023cited by 24position: middledoi
SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets
eLife 2021cited by 140position: middledoi
Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells
Nature Microbiology 2021cited by 66position: middledoi
Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase
Journal of Virology 2020cited by 55position: lastdoi
Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism
Biochemical and Biophysical Research Communications 2020cited by 16position: lastdoi
Structure of the human metapneumovirus polymerase phosphoprotein complex
Nature 2019cited by 135position: lastdoi
Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N<sup>1</sup>G37) Methyltransferase (TrmD) Inhibitors
ACS Infectious Diseases 2019cited by 54position: middledoi
Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis
Journal of Molecular Biology 2019cited by 11position: middledoi
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
Nucleic Acids Research 2017cited by 82position: middledoi
Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis
Nature Communications 2017cited by 65position: middledoi
The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production
PLoS Pathogens 2016cited by 94position: middledoi
Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in<i>Pseudomonas aeruginosa</i>
Nucleic Acids Research 2016cited by 62position: middledoi
A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication
PLoS Pathogens 2015cited by 259position: middledoi
Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope
Cell 2015cited by 138position: middledoi
Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)
Proceedings of the National Academy of Sciences 2015cited by 106position: middledoi
The C-terminal 50 Amino Acid Residues of Dengue NS3 Protein Are Important for NS3-NS5 Interaction and Viral Replication
Journal of Biological Chemistry 2014cited by 144position: middledoi
Structural Insights into the Regulatory Mechanism of the Response Regulator RocR from Pseudomonas aeruginosa in Cyclic Di-GMP Signaling
Journal of Bacteriology 2012cited by 63position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Yee Hwa Wong · Nanyang Technological University6 papers (2015–2023)Subhash G. Vasudevan · National University of Singapore6 papers (2014–2020)Peter C. Dedon · Massachusetts Institute of Technology5 papers (2016–2020)Abbas El Sahili · Nanyang Technological University5 papers (2017–2020)Dahai Luo · Affiliated Hospital of Zunyi Medical College5 papers (2014–2017)Kitti Wing Ki Chan · National University of Singapore5 papers (2014–2020)Yok Hian Chionh · National University of Singapore4 papers (2016–2019)Yongqian Zhao · National University of Singapore4 papers (2014–2016)Wenhe Zhong · Nanyang Technological University4 papers (2017–2020)Eng Eong Ooi · Duke-NUS Medical School3 papers (2014–2016)Moon Y. F. Tay · National University of Singapore3 papers (2014–2016)Xinlei Qian · National University of Singapore3 papers (2019–2023)Qixu Cai · Xiamen University3 papers (2017–2020)Malcolm D. Walkinshaw · University of Edinburgh3 papers (2017–2020)Linda A. Fothergill‐Gilmore · University of Edinburgh3 papers (2017–2020)Meng Yuan · Ministry of Education of the People's Republic of China3 papers (2017–2020)Wint Wint Phoo · Nanyang Technological University2 papers (2015–2017)Firdaus Samsudin · University of Southampton2 papers (2021–2023)Pei‐Yong Shi · First Affiliated Hospital of Nanchang University2 papers (2015–2015)Nikhil Kumar Tulsian · National University of Singapore2 papers (2021–2023)