Area of research
Public Health, Environmental and Occupational Health · Infectious Diseases
Research interest
Research interests include Biology, Dengue virus, Virology, Dengue fever, Viral replication, and RNA.
Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein
Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase
Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation
Current Status of Dengue Therapeutics Research and Development
Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication
The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production
Novel antiviral activity of bromocriptine against dengue virus replication
Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients
A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication
Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)
Animal models for studying dengue pathogenesis and therapy
Structural insight and flexible features of NS5 proteins from all four serotypes of<i>Dengue virus</i>in solution
The C-terminal 50 Amino Acid Residues of Dengue NS3 Protein Are Important for NS3-NS5 Interaction and Viral Replication
Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo
Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation
Sulfated Polysaccharide, Curdlan Sulfate, Efficiently Prevents Entry/Fusion and Restricts Antibody-Dependent Enhancement of Dengue Virus Infection In Vitro: A Possible Candidate for Clinical Application