Area of research
Molecular Biology · Oncology
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Fibroblast Growth Factor Research, PI3K/AKT/mTOR signaling in cancer, and Phagocytosis and Immune Regulation.
PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with <i>PIK3CA</i> -Mutated Solid Tumors and in Preclinical Models
RIT1M90I Is a Driver of Lung Adenocarcinoma Tumorigenesis and Resistance to Targeted Therapy
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
SHP2: A Pleiotropic Target at the Interface of Cancer and Its Microenvironment
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution
MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype
Abstract LB-034: Myc instructs and maintains pancreatic adenocarcinoma phenotype
Myc Cooperates with Ras by Programming Inflammation and Immune Suppression
Ibrutinib Exerts Potent Antifibrotic and Antitumor Activities in Mouse Models of Pancreatic Adenocarcinoma
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis