Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, DNA Repair Mechanisms, and Genetics and Neurodevelopmental Disorders.
Geographic and age variations in mutational processes in colorectal cancer
The mutagenic forces shaping the genomes of lung cancer in never smokers
The complexity of tobacco smoke-induced mutagenesis in head and neck cancer
Long-Term Latency of Highly Mutated Cells in Normal Mouse Skin Is Reversed by Exposure to Tumor Promoters and Chronic Tissue Damage
APOBEC affects tumor evolution and age at onset of lung cancer in smokers
HRProfiler Detects Homologous Recombination Deficiency in Breast and Ovarian Cancers Using Whole-Genome and Whole-Exome Sequencing Data
Geographic variation of mutagenic exposures in kidney cancer genomes
Deep Learning Artificial Intelligence Predicts Homologous Recombination Deficiency and Platinum Response From Histologic Slides
Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer
Topography of mutational signatures in human cancer
Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator
Author Correction: Pan-cancer analysis of whole genomes
Author Correction: The repertoire of mutational signatures in human cancer
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor
Mechanisms of APOBEC3 mutagenesis in human cancer cells
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours
Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence
The repertoire of mutational signatures in human cancer
Pan-cancer analysis of whole genomes
Comprehensive molecular characterization of mitochondrial genomes in human cancers
Divergent mutational processes distinguish hypoxic and normoxic tumours
SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events