Area of research
Immunology · Endocrinology, Diabetes and Metabolism
Research interest
Research interests include Immunodeficiency and Autoimmune Disorders, Adrenal Hormones and Disorders, Immune Cell Function and Interaction, and Diabetes and associated disorders.
Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function
Immune dynamics throughout life in relation to sex hormones and perspectives gained from gender-affirming hormone therapy
Human LY9 governs CD4 <sup>+</sup> T cell IFN-γ immunity to <i>Mycobacterium tuberculosis</i>
Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis
Evaluating <scp>IL1RA</scp>‐Autoantibodies Across <scp>SARS</scp>‐<scp>CoV</scp>‐2‐Related Diseases
Immune system adaptation during gender-affirming testosterone treatment
FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants
Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases
Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals
Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation
IL-7–dependent and –independent lineages of IL-7R–dependent human T cells
Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies
Impaired thymic AIRE expression underlies autoantibodies against type I IFNs in humans with inborn errors of the alternative NF-κB pathway
Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome
Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq
Sex dimorphism in the tumor microenvironment – From bench to bedside and back
Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19
Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies
GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibility
Severe COVID-19 in an APS1 patient with interferon autoantibodies treated with plasmapheresis
X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia
The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19
Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1
Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1
Transglutaminase 4 as a prostate autoantigen in male subfertility