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Likun Du

Karolinska Institutet · SE
Area of research
Immunology · Infectious Diseases
Research interest
Research interests include Immunodeficiency and Autoimmune Disorders, SARS-CoV-2 and COVID-19 Research, DNA Repair Mechanisms, and T-cell and B-cell Immunology.
h-index
37
citations
4,244
works
89
NIH funding
primary concept
email

Recent publications

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages
Proceedings of the National Academy of Sciences 2024cited by 38position: middledoi
SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency
The Journal of Experimental Medicine 2024cited by 20position: middledoi
Orientation Regulation of Class-switch Recombination in Human B Cells
The Journal of Immunology 2024cited by 8position: firstdoi
Causal relationship between hypothyroidism and coronary atherosclerotic cardiovascular disease: a bidirectional two-sample Mendelian randomization
Frontiers in Cardiovascular Medicine 2024cited by 6position: lastdoi
Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant
Nature Communications 2022cited by 166position: middledoi
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant
BMC Medicine 2022cited by 86position: middledoi
Human T-bet governs the generation of a distinct subset of CD11c <sup>high</sup> CD21 <sup>low</sup> B cells
Science Immunology 2022cited by 82position: middledoi
Immunity to SARS-CoV-2 up to 15 months after infection
iScience 2022cited by 79position: middledoi
Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome
Journal of Clinical Immunology 2022cited by 76position: middledoi
Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19
Journal of Allergy and Clinical Immunology 2022cited by 42position: middledoi
Genomic characterization of lymphomas in patients with inborn errors of immunity
Blood Advances 2022cited by 38position: middledoi
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6–8 months after the infection
Med 2021cited by 202position: middledoi
SARS-CoV-2–specific B- and T-cell immunity in a population-based study of young Swedish adults
Journal of Allergy and Clinical Immunology 2021cited by 56position: middledoi
X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia
Journal of Clinical Immunology 2021cited by 45position: middledoi
Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma
Cell Death and Disease 2021cited by 33position: middledoi
APRIL-dependent lifelong plasmacyte maintenance and immunoglobulin production in humans
Journal of Allergy and Clinical Immunology 2020cited by 58position: middledoi
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining
Nature Communications 2018cited by 68position: middledoi
<i>EXTL3</i> mutations cause skeletal dysplasia, immune deficiency, and developmental delay
The Journal of Experimental Medicine 2017cited by 84position: middledoi
Combined immunodeficiency and Epstein-Barr virus–induced B cell malignancy in humans with inherited CD70 deficiency
The Journal of Experimental Medicine 2016cited by 151position: middledoi
Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1-dependent immune deficiencies
Blood 2016cited by 47position: middledoi
Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia
The Journal of Experimental Medicine 2015cited by 292position: middledoi
Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells
Proceedings of the National Academy of Sciences 2014cited by 37position: middledoi
IgA subclass switch recombination in human mucosal and systemic immune compartments
Mucosal Immunology 2013cited by 94position: middledoi
Deleterious Mutations in LRBA Are Associated with a Syndrome of Immune Deficiency and Autoimmunity
The American Journal of Human Genetics 2012cited by 520position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Qiang Pan‐Hammarström · Karolinska Institutet9 papers (2013–2024)Jean‐Laurent Casanova · Tehran University of Medical Sciences4 papers (2015–2022)Hassan Abolhassani · University of Bonn4 papers (2021–2024)Lennart Hammarström · Karolinska Institutet4 papers (2021–2024)Qian Zhang · BGI Group (China)3 papers (2021–2022)Shen‐Ying Zhang · Inserm3 papers (2021–2022)Olle Kämpe · Karolinska University Hospital3 papers (2021–2022)Harold Marcotte · Karolinska Institutet3 papers (2021–2022)Paul Bastard · Inserm3 papers (2021–2022)Fanglei Zuo · Karolinska Institutet3 papers (2021–2022)Luigi D. Notarangelo · National Institutes of Health3 papers (2014–2016)Nils Landegren · Uppsala University3 papers (2021–2022)Maribel Aranda‐Guillén · Karolinska Institutet3 papers (2021–2022)Mirjam van der Burg · Rockefeller University2 papers (2014–2024) · 2 papers (2014–2016) · 2 papers (2021–2022) · 2 papers (2022–2022)Xiaofei Ye · Karolinska Institutet2 papers (2021–2024) · 2 papers (2015–2016) · 2 papers (2021–2022)