Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Acute Myeloid Leukemia Research, Protein Degradation and Inhibitors, and Lung Cancer Treatments and Mutations.
CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival
The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia
The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia
Functional characterization of a PROTAC directed against BRAF mutant V600E
A drug discovery platform to identify compounds that inhibit EGFR triple mutants
Discovery of an MLLT1/3 YEATS Domain Chemical Probe
Interrogation of Functional Cell-Surface Markers Identifies CD151 Dependency in High-Grade Serous Ovarian Cancer
WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma
BRAIN TUMOUR INITIATING CELLS AND TARGETING STAT3 ONCOGENIC SIGNALLING IN GBM
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors