Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Bioinformatics and Genomic Networks, Gene Regulatory Network Analysis, Single-cell and spatial transcriptomics, and Gene expression and cancer classification.
Exploring the role of large language models in the scientific method: from hypothesis to discovery
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression
Benchmarking cross-species single-cell RNA-seq data integration methods: towards a cell type tree of life
Whispering LLaMA: A Cross-Modal Generative Error Correction Framework for Speech Recognition
Deep neural network prediction of genome-wide transcriptome signatures – beyond the Black-box
A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts
STATegra: Multi-Omics Data Integration – A Conceptual Scheme With a Bioinformatics Pipeline
Predicting anti-PD-1 responders in malignant melanoma from the frequency of S100A9+ monocytes in the blood
Harmonization of quality metrics and power calculation in multi-omic studies
Deriving disease modules from the compressed transcriptional space embedded in a deep autoencoder
Building gene regulatory networks from scATAC-seq and scRNA-seq using Linked Self Organizing Maps
Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
A Review of Graph and Network Complexity from an Algorithmic Information Perspective
Causal deconvolution by algorithmic generative models
Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3
Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients
Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis
Low-algorithmic-complexity entropy-deceiving graphs
Hypermethylation of <i>MIR21</i> in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes
Human macrophages induce CD4<sup>+</sup>Foxp3<sup>+</sup> regulatory T cells via binding and re‐release of TGF‐β
Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate
Proposals for enhanced health risk assessment and stratification in an integrated care scenario
High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis
Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR
VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients
IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3