Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Extracellular vesicles in disease, RNA Interference and Gene Delivery, MicroRNA in disease regulation, and Cell Adhesion Molecules Research.
Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors
Extracellular Histones as Exosome Membrane Proteins Regulated by Cell Stress
T cell toxicity induced by tigecycline binding to the mitochondrial ribosome
Screening scaffold proteins for improved functional delivery of luminal proteins using engineered extracellular vesicles
Antibody-displaying extracellular vesicles for targeted cancer therapy
Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics
Novel Endogenous Engineering Platform for Robust Loading and Delivery of Functional mRNA by Extracellular Vesicles
Extracellular vesicles originating from melanoma cells promote dysregulation in haematopoiesis as a component of cancer immunoediting
Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles
Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models
Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles
Extracellular vesicles are the primary source of blood‐borne tumour‐derived mutant <i>KRAS</i> DNA early in pancreatic cancer
Extracellular vesicles as drug delivery systems: Why and how?
Quantification of extracellular vesicles <i>in vitro</i> and <i>in vivo</i> using sensitive bioluminescence imaging
Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and single particle imaging
Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography
Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
Serum‐free culture alters the quantity and protein composition of neuroblastoma‐derived extracellular vesicles
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome
Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides
Systemic exosomal siRNA delivery reduced alpha‐synuclein aggregates in brains of transgenic mice
Diagnostic value of abdominal drainage in individual risk assessment of pancreatic fistula following pancreaticoduodenectomy