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Pieter Vader

Utrecht University · NL
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Extracellular vesicles in disease, RNA Interference and Gene Delivery, MicroRNA in disease regulation, and Advanced biosensing and bioanalysis techniques.
h-index
53
citations
31,869
works
138
NIH funding
primary concept
email

Recent publications

Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors
Nature Communications 2025cited by 66position: middledoi
Nature-inspired platform nanotechnology for RNA delivery to myeloid cells and their bone marrow progenitors
Nature Nanotechnology 2025cited by 43position: middledoi
Integrin beta 1 and fibronectin mediate extracellular vesicle uptake and functional RNA delivery
Journal of Biological Chemistry 2025cited by 17position: lastdoi
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
Advanced Healthcare Materials 2025cited by 13position: middledoi
A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release
Nature Communications 2025cited by 11position: middledoi
Modulating binding affinity of aptamer-based loading constructs enhances extracellular vesicle-mediated CRISPR/Cas9 delivery
Journal of Controlled Release 2025cited by 6position: middledoi
Size matters: Functional differences of small extracellular vesicle subpopulations in cardiac repair responses
Journal of Extracellular Vesicles 2024cited by 42position: lastdoi
Cardiac delivery of modified mRNA using lipid nanoparticles: Cellular targets and biodistribution after intramyocardial administration
Journal of Controlled Release 2024cited by 39position: lastdoi
Inter‐laboratory multiplex bead‐based surface protein profiling of MSC‐derived EV preparations identifies MSC‐EV surface marker signatures
Journal of Extracellular Vesicles 2024cited by 37position: middledoi
Extracellular vesicle‐mediated delivery of CRISPR/Cas9 ribonucleoprotein complex targeting proprotein convertase subtilisin‐kexin type 9 (Pcsk9) in primary mouse hepatocytes
Journal of Extracellular Vesicles 2024cited by 33position: middledoi
Scalable purification of extracellular vesicles with high yield and purity using multimodal flowthrough chromatography
Journal of Extracellular Biology 2024cited by 27position: lastdoi
Hypoxia and TNF‐alpha modulate extracellular vesicle release from human induced pluripotent stem cell‐derived cardiomyocytes
Journal of Extracellular Vesicles 2024cited by 16position: middledoi
Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process
Communications Biology 2023cited by 69position: middledoi
TOP-EVs: Technology of Protein delivery through Extracellular Vesicles is a versatile platform for intracellular protein delivery
Journal of Controlled Release 2023cited by 60position: middledoi
Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration
ACS Nano 2023cited by 40position: middledoi
Cardiac progenitor cell-derived extracellular vesicles promote angiogenesis through both associated- and co-isolated proteins
Communications Biology 2023cited by 25position: middledoi
Challenges and directions in studying cell–cell communication by extracellular vesicles
Nature Reviews Molecular Cell Biology 2022cited by 1,159position: lastdoi
Identification of storage conditions stabilizing extracellular vesicles preparations
Journal of Extracellular Vesicles 2022cited by 385position: middledoi
Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles
Cardiovascular Research 2022cited by 160position: middledoi
Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement
Endocrine Reviews 2022cited by 117position: middledoi
Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles
Journal of Controlled Release 2022cited by 103position: middledoi
Functional siRNA Delivery by Extracellular Vesicle–Liposome Hybrid Nanoparticles
Advanced Healthcare Materials 2021cited by 202position: lastdoi
Influence of short term storage conditions, concentration methods and excipients on extracellular vesicle recovery and function
European Journal of Pharmaceutics and Biopharmaceutics 2021cited by 68position: lastdoi
Illuminating RNA trafficking and functional delivery by extracellular vesicles
Advanced Drug Delivery Reviews 2021cited by 67position: lastdoi
Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering
Molecular Therapy — Nucleic Acids 2021cited by 31position: middledoi
Hydrogel‐Induced Cell Membrane Disruptions Enable Direct Cytosolic Delivery of Membrane‐Impermeable Cargo
Advanced Materials 2021cited by 19position: middledoi
Extracellular vesicles as drug delivery systems: Why and how?
Advanced Drug Delivery Reviews 2020cited by 1,181position: lastdoi
Extracellular Vesicle-Associated Proteins in Tissue Repair
Trends in Cell Biology 2020cited by 209position: lastdoi
A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA
Nature Communications 2020cited by 190position: lastdoi
A post-insertion strategy for surface functionalization of bacterial and mammalian cell-derived extracellular vesicles
Biochimica et Biophysica Acta (BBA) - General Subjects 2020cited by 24position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Raymond M. Schiffelers · Utrecht University21 papers (2012–2025)Olivier G. de Jong · Utrecht University18 papers (2012–2025)Joost P. G. Sluijter · Royal Netherlands Academy of Arts and Sciences18 papers (2018–2024)Samir EL Andaloussi · Karolinska University Hospital12 papers (2015–2025)Matthew J. A. Wood · University of Oxford10 papers (2014–2024)Sander A. A. Kooijmans · Utrecht University7 papers (2016–2025)Imre Mäger · Zogenix (United States)7 papers (2015–2020)Simonides Immanuel van de Wakker · Utrecht University7 papers (2021–2024)Emma A. Mol · Utrecht University6 papers (2016–2023)Marieke T. Roefs · Utrecht University6 papers (2019–2024)Saskia C.A. de Jager · University Medical Center Utrecht5 papers (2022–2024)Yi Lee · Karolinska Institutet5 papers (2015–2022)Zhiyong Lei · Utrecht University5 papers (2019–2024)Willemijn S. de Voogt · Utrecht University5 papers (2021–2025)Omnia M. Elsharkasy · Utrecht University4 papers (2020–2025)Oscar P. B. Wiklander · Karolinska University Hospital4 papers (2015–2022)André Görgens · Karolinska University Hospital4 papers (2021–2024) · 4 papers (2016–2024)Joel Z. Nordin · Karolinska University Hospital4 papers (2015–2020)Linglei Jiang · Johns Hopkins Medicine3 papers (2019–2020)