Area of research
Physiology · Psychiatry and Mental health
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Genetic Associations and Epidemiology, and Bioinformatics and Genomic Networks.
Sex differences on tau, astrocytic, and neurodegenerative plasma biomarkers
A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes
Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non‐genetic risk factors for Alzheimer's disease among Asian Americans and Canadians
APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response
Optimal blood tau species for the detection of Alzheimer’s disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study
Cross‐sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease
Using community-based geographical information system (GIS) to recruit older Asian Americans in an Alzheimer’s disease study
African ancestry GWAS of dementia in a large military cohort identifies significant risk loci
Genome‐wide association and multi‐omics studies identify <i>MGMT</i> as a novel risk gene for Alzheimer's disease among women
Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease
Protein phosphatase 2A and complement component 4 are linked to the protective effect of <i>APOE</i> ɛ2 for Alzheimer's disease
Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer’s disease neuropathology and regional tau at autopsy
Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90
The Asian Cohort for Alzheimer’s Disease (ACAD) Pilot Study
Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease
Cytokine Levels in Human Vitreous in Proliferative Diabetic Retinopathy
Plasma p‐tau<sub>181</sub> shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau
The Asian Cohort for Alzheimer’s Disease (ACAD) study
Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype
Neurofilament light chain in the vitreous humor of the eye
Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract
Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report
APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer’s Disease Risk in a Multiracial Sample
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by <i>APOE</i> Genotype
Association of Cognitive Function with Amyloid-β and Tau Proteins in the Vitreous Humor
Comparison of methods for multivariate gene-based association tests for complex diseases using common variants
CpG‐related SNPs in the MS4A region have a dose‐dependent effect on risk of late–onset Alzheimer disease
Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer’s disease
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer’s Disease Sequencing Project